BDBM50054036 (E)-6-(6-Hydroxy-2-methoxy-3,4-dimethyl-phenyl)-4-methyl-hex-4-enoic acid::CHEMBL423888

SMILES: COc1c(C)c(C)cc(O)c1C\C=C(/C)CCC(O)=O

InChI Key: InChIKey=YZSVFQLDBYYYRV-BJMVGYQFSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50054036   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2) (Homo sapiens (Human))	BDBM50054036 ((E)-6-(6-Hydroxy-2-methoxy-3,4-dimethyl-phenyl)-4-...) Show SMILES COc1c(C)c(C)cc(O)c1C\C=C(/C)CCC(O)=O Show InChI InChI=1S/C16H22O4/c1-10(6-8-15(18)19)5-7-13-14(17)9-11(2)12(3)16(13)20-4/h5,9,17H,6-8H2,1-4H3,(H,18,19)/b10-5+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.18E+4	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Inhibition of human recombinant inosine monophosphate dehydrogenase type II .				J Med Chem 39: 4181-96 (1996) Article DOI: 10.1021/jm9603633 BindingDB Entry DOI: 10.7270/Q2668C8Q
					More data for this Ligand-Target Pair