BDBM50054221 CHEMBL419636::N,N-Dibutyl-6-methyl-N'-(2,4,6-trimethyl-phenyl)-[1,3,5]triazine-2,4-diamine
SMILES: CCCCN(CCCC)c1nc(C)nc(Nc2c(C)cc(C)cc2C)n1
InChI Key: InChIKey=YDIVVGPEMJITAB-UHFFFAOYSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Corticotropin releasing factor receptor 1 (Homo sapiens (Human)) | BDBM50054221 (CHEMBL419636 | N,N-Dibutyl-6-methyl-N'-(2,4,6-trim...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 490 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Wollongong Curated by ChEMBL | Assay Description Inhibition of [125I]-CRH binding to human Corticotropin releasing factor receptor 1. | J Med Chem 42: 2351-7 (1999) Article DOI: 10.1021/jm9900117 BindingDB Entry DOI: 10.7270/Q2WS8SF0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Corticotropin releasing factor receptor 1 (Homo sapiens (Human)) | BDBM50054221 (CHEMBL419636 | N,N-Dibutyl-6-methyl-N'-(2,4,6-trim...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 490 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Biosciences Curated by ChEMBL | Assay Description Inhibition of [125I]-CRF binding to human corticotropin releasing factor receptor 1 | J Med Chem 39: 4354-7 (1996) Article DOI: 10.1021/jm960148m BindingDB Entry DOI: 10.7270/Q2DR2TK7 | |||||||||||
More data for this Ligand-Target Pair |