BDBM50054225 CHEMBL306618::N-Cyclopropylmethyl-6-methyl-N-propyl-N'-(2,4,6-trimethyl-phenyl)-[1,3,5]triazine-2,4-diamine

SMILES: CCCN(CC1CC1)c1nc(C)nc(Nc2c(C)cc(C)cc2C)n1

InChI Key: InChIKey=FBXLFDORXAEASX-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50054225   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50054225 (CHEMBL306618 | N-Cyclopropylmethyl-6-methyl-N-prop...) Show SMILES CCCN(CC1CC1)c1nc(C)nc(Nc2c(C)cc(C)cc2C)n1 Show InChI InChI=1S/C20H29N5/c1-6-9-25(12-17-7-8-17)20-22-16(5)21-19(24-20)23-18-14(3)10-13(2)11-15(18)4/h10-11,17H,6-9,12H2,1-5H3,(H,21,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	57	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Inhibition of [125I]-CRF binding to human corticotropin releasing factor receptor 1				J Med Chem 39: 4354-7 (1996) Article DOI: 10.1021/jm960148m BindingDB Entry DOI: 10.7270/Q2DR2TK7
					More data for this Ligand-Target Pair
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50054225 (CHEMBL306618 | N-Cyclopropylmethyl-6-methyl-N-prop...) Show SMILES CCCN(CC1CC1)c1nc(C)nc(Nc2c(C)cc(C)cc2C)n1 Show InChI InChI=1S/C20H29N5/c1-6-9-25(12-17-7-8-17)20-22-16(5)21-19(24-20)23-18-14(3)10-13(2)11-15(18)4/h10-11,17H,6-9,12H2,1-5H3,(H,21,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	57	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Wollongong Curated by ChEMBL					Assay Description Inhibition of [125I]-CRH binding to human Corticotropin releasing factor receptor 1.				J Med Chem 42: 2351-7 (1999) Article DOI: 10.1021/jm9900117 BindingDB Entry DOI: 10.7270/Q2WS8SF0
					More data for this Ligand-Target Pair
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50054225 (CHEMBL306618 | N-Cyclopropylmethyl-6-methyl-N-prop...) Show SMILES CCCN(CC1CC1)c1nc(C)nc(Nc2c(C)cc(C)cc2C)n1 Show InChI InChI=1S/C20H29N5/c1-6-9-25(12-17-7-8-17)20-22-16(5)21-19(24-20)23-18-14(3)10-13(2)11-15(18)4/h10-11,17H,6-9,12H2,1-5H3,(H,21,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	57	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Inhibition of [125I]-CRF binding to human Corticotropin releasing factor receptor 1 tested at 6-12 doses				J Med Chem 39: 4358-60 (1996) Article DOI: 10.1021/jm960149e BindingDB Entry DOI: 10.7270/Q29022V6
					More data for this Ligand-Target Pair