BDBM50054383 2-{3-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-propyl}-tetrahydro-imidazo[1,5-a]pyridine-1,3-dione::CHEMBL45007::cid_3587301

SMILES: Oc1c2CCCCn2c(=O)n1CCCN1CCN(CC1)c1ccc(F)cc1

InChI Key: InChIKey=UNINGNCNGLMMRX-UHFFFAOYSA-N

Data: 3 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50054383   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50054383 (2-{3-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-propyl}-...) Show SMILES Oc1c2CCCCn2c(=O)n1CCCN1CCN(CC1)c1ccc(F)cc1 Show InChI InChI=1S/C20H27FN4O2/c21-16-5-7-17(8-6-16)23-14-12-22(13-15-23)9-3-11-25-19(26)18-4-1-2-10-24(18)20(25)27/h5-8,26H,1-4,9-15H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	598	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Binding affinity towards rat 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand.				J Med Chem 39: 4439-50 (1996) Article DOI: 10.1021/jm960416g BindingDB Entry DOI: 10.7270/Q2WS8SBN
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50054383 (2-{3-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-propyl}-...) Show SMILES Oc1c2CCCCn2c(=O)n1CCCN1CCN(CC1)c1ccc(F)cc1 Show InChI InChI=1S/C20H27FN4O2/c21-16-5-7-17(8-6-16)23-14-12-22(13-15-23)9-3-11-25-19(26)18-4-1-2-10-24(18)20(25)27/h5-8,26H,1-4,9-15H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	598	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Tested in vitro for binding affinity by measuring its ability to inhibit [3H]8-OH-DPAT binding at 5-hydroxytryptamine 1A receptor in rat cerebral cor...				J Med Chem 40: 1648-56 (1997) Article DOI: 10.1021/jm960744g BindingDB Entry DOI: 10.7270/Q2K35V96
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50054383 (2-{3-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-propyl}-...) Show SMILES Oc1c2CCCCn2c(=O)n1CCCN1CCN(CC1)c1ccc(F)cc1 Show InChI InChI=1S/C20H27FN4O2/c21-16-5-7-17(8-6-16)23-14-12-22(13-15-23)9-3-11-25-19(26)18-4-1-2-10-24(18)20(25)27/h5-8,26H,1-4,9-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Binding affinity towards dopamine receptor D2 using [3H]-raclopride radioligand.				J Med Chem 39: 4439-50 (1996) Article DOI: 10.1021/jm960416g BindingDB Entry DOI: 10.7270/Q2WS8SBN
					More data for this Ligand-Target Pair
Hsf1 protein (Mus musculus)	BDBM50054383 (2-{3-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-propyl}-...) Show SMILES Oc1c2CCCCn2c(=O)n1CCCN1CCN(CC1)c1ccc(F)cc1 Show InChI InChI=1S/C20H27FN4O2/c21-16-5-7-17(8-6-16)23-14-12-22(13-15-23)9-3-11-25-19(26)18-4-1-2-10-24(18)20(25)27/h5-8,26H,1-4,9-15H2	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	>2.60E+5	n/a	n/a	n/a	n/a
Broad Institute Curated by PubChem BioAssay					Assay Description Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2P55KXK
					More data for this Ligand-Target Pair