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BDBM50054662 8-(5-Cyclopropyl-[1,2,4]oxadiazol-3-yl)-4,4-dimethyl-4,5-dihydro-7H-6a,9,10a-triaza-cyclopenta[a]phenalen-6-one::CHEMBL343489

SMILES: CC1(C)CC(=O)N2Cc3c(ncn3-c3cccc1c23)-c1noc(n1)C1CC1

InChI Key: InChIKey=ZSDLFZKXYVEZDI-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50054662   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
GABA receptor alpha-6/beta-2/gamma-2 subunit


(RAT-Rattus norvegicus (Rat))		BDBM50054662
PNG
(8-(5-Cyclopropyl-[1,2,4]oxadiazol-3-yl)-4,4-dimeth...)
Show SMILES CC1(C)CC(=O)N2Cc3c(ncn3-c3cccc1c23)-c1noc(n1)C1CC1
Show InChI InChI=1S/C20H19N5O2/c1-20(2)8-15(26)24-9-14-16(18-22-19(27-23-18)11-6-7-11)21-10-25(14)13-5-3-4-12(20)17(13)24/h3-5,10-11H,6-9H2,1-2H3
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PC cid
PC sid
UniChem

Similars
Article
PubMed
>589n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-Ro- 15-4513 from alpha6 beta2 gamma2 subunits of Rat GABA-A receptor expressed in Sf-9 insect cell membranes

J Med Chem 39: 4654-66 (1996)


Article DOI: 10.1021/jm960401i
BindingDB Entry DOI: 10.7270/Q20K27NN
More data for this
Ligand-Target Pair