BDBM50054679 2-Methyl-4-[(E)-2-(4-nitro-phenyl)-vinyl]-6-phenyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 5-benzyl ester 3-ethyl ester::CHEMBL357837
SMILES: CCOC(=[OH+])C1=C(C)N=C(\C(C1\C=C\c1ccc(cc1)[N+]([O-])=O)=C(\[O-])OCc1ccccc1)c1ccccc1
InChI Key: InChIKey=JTRVEBOHWQQTPF-JSGBXJPQSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Adenosine receptor A3 (Homo sapiens (Human)) | BDBM50054679 (2-Methyl-4-[(E)-2-(4-nitro-phenyl)-vinyl]-6-phenyl...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 72 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes Curated by ChEMBL | Assay Description Binding affinity against cloned human adenosine A3 receptor by radioligand binding assay using [125I]-AB-MECA. | J Med Chem 39: 4667-75 (1996) Article DOI: 10.1021/jm960457c BindingDB Entry DOI: 10.7270/Q2VQ33BG | |||||||||||
More data for this Ligand-Target Pair |