BDBM50054804 (1S,2R)-2-(1-Amino-ethyl)-1-phenyl-cyclopropanecarboxylic acid diethylamide::CHEMBL330958

SMILES: CCN(CC)C(=O)[C@]1(C[C@H]1C(C)N)c1ccccc1

InChI Key: InChIKey=JZWQQSJMOZMVFS-OTZYVQGASA-N

Data: 4 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50054804   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50054804 ((1S,2R)-2-(1-Amino-ethyl)-1-phenyl-cyclopropanecar...) Show SMILES CCN(CC)C(=O)[C@]1(C[C@H]1C(C)N)c1ccccc1 Show InChI InChI=1S/C16H24N2O/c1-4-18(5-2)15(19)16(11-14(16)12(3)17)13-9-7-6-8-10-13/h6-10,12,14H,4-5,11,17H2,1-3H3/t12?,14-,16+/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hokkaido University Curated by ChEMBL					Assay Description Inhibition of [3H]-paroxetine binding on serotonin transporter of rat cerebral cortical synaptic membrane				J Med Chem 39: 4844-52 (1997) Article DOI: 10.1021/jm960495w BindingDB Entry DOI: 10.7270/Q2M907R2
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50054804 ((1S,2R)-2-(1-Amino-ethyl)-1-phenyl-cyclopropanecar...) Show SMILES CCN(CC)C(=O)[C@]1(C[C@H]1C(C)N)c1ccccc1 Show InChI InChI=1S/C16H24N2O/c1-4-18(5-2)15(19)16(11-14(16)12(3)17)13-9-7-6-8-10-13/h6-10,12,14H,4-5,11,17H2,1-3H3/t12?,14-,16+/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hokkaido University Curated by ChEMBL					Assay Description Inhibition of Serotonin transporter in cerebral cortical synaptic membrane of rats using [3H]-paroxetine				J Med Chem 41: 3507-14 (1998) Article DOI: 10.1021/jm980238m BindingDB Entry DOI: 10.7270/Q2000175
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50054804 ((1S,2R)-2-(1-Amino-ethyl)-1-phenyl-cyclopropanecar...) Show SMILES CCN(CC)C(=O)[C@]1(C[C@H]1C(C)N)c1ccccc1 Show InChI InChI=1S/C16H24N2O/c1-4-18(5-2)15(19)16(11-14(16)12(3)17)13-9-7-6-8-10-13/h6-10,12,14H,4-5,11,17H2,1-3H3/t12?,14-,16+/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hokkaido University Curated by ChEMBL					Assay Description Inhibition of Serotonin transporter in cerebral cortical synaptic membrane of rats using [3H]-paroxetine				J Med Chem 41: 3507-14 (1998) Article DOI: 10.1021/jm980238m BindingDB Entry DOI: 10.7270/Q2000175
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50054804 ((1S,2R)-2-(1-Amino-ethyl)-1-phenyl-cyclopropanecar...) Show SMILES CCN(CC)C(=O)[C@]1(C[C@H]1C(C)N)c1ccccc1 Show InChI InChI=1S/C16H24N2O/c1-4-18(5-2)15(19)16(11-14(16)12(3)17)13-9-7-6-8-10-13/h6-10,12,14H,4-5,11,17H2,1-3H3/t12?,14-,16+/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hokkaido University Curated by ChEMBL					Assay Description Inhibition of [3H]-paroxetine binding on serotonin transporter of rat cerebral cortical synaptic membrane				J Med Chem 39: 4844-52 (1997) Article DOI: 10.1021/jm960495w BindingDB Entry DOI: 10.7270/Q2M907R2
					More data for this Ligand-Target Pair
NMDA receptor subunit 2C (GluN2C) (Rattus norvegicus (Rat))	BDBM50054804 ((1S,2R)-2-(1-Amino-ethyl)-1-phenyl-cyclopropanecar...) Show SMILES CCN(CC)C(=O)[C@]1(C[C@H]1C(C)N)c1ccccc1 Show InChI InChI=1S/C16H24N2O/c1-4-18(5-2)15(19)16(11-14(16)12(3)17)13-9-7-6-8-10-13/h6-10,12,14H,4-5,11,17H2,1-3H3/t12?,14-,16+/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hokkaido University Curated by ChEMBL					Assay Description Concentration required to inhibit of N-methyl-D-aspartic acid (NMDA) receptor produced by oocytes				J Med Chem 39: 4844-52 (1997) Article DOI: 10.1021/jm960495w BindingDB Entry DOI: 10.7270/Q2M907R2
					More data for this Ligand-Target Pair