BDBM50054996 1-[2-(6-Methoxy-3,4-dihydro-naphthalen-2-yl)-ethyl]-4-phenyl-piperazine::CHEMBL357176

SMILES: COc1ccc2C=C(CCN3CCN(CC3)c3ccccc3)CCc2c1

InChI Key: InChIKey=HTCBQRGEAMMAAA-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50054996   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50054996 (1-[2-(6-Methoxy-3,4-dihydro-naphthalen-2-yl)-ethyl...) Show SMILES COc1ccc2C=C(CCN3CCN(CC3)c3ccccc3)CCc2c1 |t:6| Show InChI InChI=1S/C23H28N2O/c1-26-23-10-9-20-17-19(7-8-21(20)18-23)11-12-24-13-15-25(16-14-24)22-5-3-2-4-6-22/h2-6,9-10,17-18H,7-8,11-16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Binding affinity towards rat Dopamine receptor D2 was evaluated using [3H]- spiroperidol as radioligand				J Med Chem 39: 4928-34 (1997) Article DOI: 10.1021/jm9604538 BindingDB Entry DOI: 10.7270/Q2ZG6SX1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50054996 (1-[2-(6-Methoxy-3,4-dihydro-naphthalen-2-yl)-ethyl...) Show SMILES COc1ccc2C=C(CCN3CCN(CC3)c3ccccc3)CCc2c1 |t:6| Show InChI InChI=1S/C23H28N2O/c1-26-23-10-9-20-17-19(7-8-21(20)18-23)11-12-24-13-15-25(16-14-24)22-5-3-2-4-6-22/h2-6,9-10,17-18H,7-8,11-16H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.20	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Binding affinity towards rat 5-hydroxytryptamine 1A receptor was evaluated using [3H]8-OH-DPAT as radioligand				J Med Chem 39: 4928-34 (1997) Article DOI: 10.1021/jm9604538 BindingDB Entry DOI: 10.7270/Q2ZG6SX1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50054996 (1-[2-(6-Methoxy-3,4-dihydro-naphthalen-2-yl)-ethyl...) Show SMILES COc1ccc2C=C(CCN3CCN(CC3)c3ccccc3)CCc2c1 |t:6| Show InChI InChI=1S/C23H28N2O/c1-26-23-10-9-20-17-19(7-8-21(20)18-23)11-12-24-13-15-25(16-14-24)22-5-3-2-4-6-22/h2-6,9-10,17-18H,7-8,11-16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Binding affinity towards rat 5-hydroxytryptamine 2A receptor was evaluated using [3H]- ketanserin as radioligand				J Med Chem 39: 4928-34 (1997) Article DOI: 10.1021/jm9604538 BindingDB Entry DOI: 10.7270/Q2ZG6SX1
					More data for this Ligand-Target Pair