BDBM50055105 CHEMBL3323596

SMILES: COc1ccccc1-c1nc2ccc(Nc3ccnc4ccccc34)cc2[nH]1

InChI Key: InChIKey=GVGDETXDTJSCMV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50055105   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50055105 (CHEMBL3323596) Show SMILES COc1ccccc1-c1nc2ccc(Nc3ccnc4ccccc34)cc2[nH]1 Show InChI InChI=1S/C23H18N4O/c1-28-22-9-5-3-7-17(22)23-26-20-11-10-15(14-21(20)27-23)25-19-12-13-24-18-8-4-2-6-16(18)19/h2-14H,1H3,(H,24,25)(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of VEGFR2 (unknown origin) using ATP/substrate peptide after 1 hr by colorimetric ELISA				Eur J Med Chem 84: 698-707 (2014) Article DOI: 10.1016/j.ejmech.2014.07.071 BindingDB Entry DOI: 10.7270/Q26Q1ZWB
					More data for this Ligand-Target Pair