BDBM50055358 2-(1-Benzyl-3-carbamoylmethyl-2-ethyl-1H-indol-5-yloxymethyl)-benzoic acid::CHEMBL342549

SMILES: CCc1c(CC(N)=O)c2cc(OCc3ccccc3C(O)=O)ccc2n1Cc1ccccc1

InChI Key: InChIKey=UKWIMPGIJCPSCG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50055358   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phospholipase A2, membrane associated (Homo sapiens (Human))	BDBM50055358 (2-(1-Benzyl-3-carbamoylmethyl-2-ethyl-1H-indol-5-y...) Show SMILES CCc1c(CC(N)=O)c2cc(OCc3ccccc3C(O)=O)ccc2n1Cc1ccccc1 Show InChI InChI=1S/C27H26N2O4/c1-2-24-23(15-26(28)30)22-14-20(33-17-19-10-6-7-11-21(19)27(31)32)12-13-25(22)29(24)16-18-8-4-3-5-9-18/h3-14H,2,15-17H2,1H3,(H2,28,30)(H,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	555	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay				J Med Chem 39: 5137-58 (1997) Article DOI: 10.1021/jm960486n BindingDB Entry DOI: 10.7270/Q2639NV0
					More data for this Ligand-Target Pair