null

SMILES: C(CN1CCN(CC1)c1ccccn1)[C@H]1CCC(=CC1)c1ccccc1

InChI Key: InChIKey=MQHGACGPMGUHSJ-HXUWFJFHSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50055724   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50055724 (1-[2-((S)-4-Phenyl-cyclohex-3-enyl)-ethyl]-4-pyrid...) Show SMILES C(CN1CCN(CC1)c1ccccn1)[C@H]1CCC(=CC1)c1ccccc1 |c:19| Show InChI InChI=1S/C23H29N3/c1-2-6-21(7-3-1)22-11-9-20(10-12-22)13-15-25-16-18-26(19-17-25)23-8-4-5-14-24-23/h1-8,11,14,20H,9-10,12-13,15-19H2/t20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	412	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Division of Warner Lambert Company Curated by ChEMBL					Assay Description In vitro binding affinity for dopamine receptor D2 on rat striatal membranes by [3H]-spiperone displacement.				J Med Chem 40: 250-9 (1997) Article DOI: 10.1021/jm960597m BindingDB Entry DOI: 10.7270/Q28W3CD4
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50055724 (1-[2-((S)-4-Phenyl-cyclohex-3-enyl)-ethyl]-4-pyrid...) Show SMILES C(CN1CCN(CC1)c1ccccn1)[C@H]1CCC(=CC1)c1ccccc1 |c:19| Show InChI InChI=1S/C23H29N3/c1-2-6-21(7-3-1)22-11-9-20(10-12-22)13-15-25-16-18-26(19-17-25)23-8-4-5-14-24-23/h1-8,11,14,20H,9-10,12-13,15-19H2/t20-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	>6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro antagonist binding affinity was determined by displacing the [3H]-SCH- in rat striatal Dopamine receptor D1				Bioorg Med Chem Lett 3: 639-644 (1993) Article DOI: 10.1016/S0960-894X(01)81245-2 BindingDB Entry DOI: 10.7270/Q2222V75
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50055724 (1-[2-((S)-4-Phenyl-cyclohex-3-enyl)-ethyl]-4-pyrid...) Show SMILES C(CN1CCN(CC1)c1ccccn1)[C@H]1CCC(=CC1)c1ccccc1 |c:19| Show InChI InChI=1S/C23H29N3/c1-2-6-21(7-3-1)22-11-9-20(10-12-22)13-15-25-16-18-26(19-17-25)23-8-4-5-14-24-23/h1-8,11,14,20H,9-10,12-13,15-19H2/t20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	82	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro agonist binding affinity was determined by displacing the [3H]N-propylnorapomorphine ([3H]NPA) in rat striatal Dopamine receptor D2				Bioorg Med Chem Lett 3: 639-644 (1993) Article DOI: 10.1016/S0960-894X(01)81245-2 BindingDB Entry DOI: 10.7270/Q2222V75
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50055724 (1-[2-((S)-4-Phenyl-cyclohex-3-enyl)-ethyl]-4-pyrid...) Show SMILES C(CN1CCN(CC1)c1ccccn1)[C@H]1CCC(=CC1)c1ccccc1 |c:19| Show InChI InChI=1S/C23H29N3/c1-2-6-21(7-3-1)22-11-9-20(10-12-22)13-15-25-16-18-26(19-17-25)23-8-4-5-14-24-23/h1-8,11,14,20H,9-10,12-13,15-19H2/t20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	412	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from rat striatal Dopamine receptor D2				Bioorg Med Chem Lett 3: 639-644 (1993) Article DOI: 10.1016/S0960-894X(01)81245-2 BindingDB Entry DOI: 10.7270/Q2222V75
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50055724 (1-[2-((S)-4-Phenyl-cyclohex-3-enyl)-ethyl]-4-pyrid...) Show SMILES C(CN1CCN(CC1)c1ccccn1)[C@H]1CCC(=CC1)c1ccccc1 |c:19| Show InChI InChI=1S/C23H29N3/c1-2-6-21(7-3-1)22-11-9-20(10-12-22)13-15-25-16-18-26(19-17-25)23-8-4-5-14-24-23/h1-8,11,14,20H,9-10,12-13,15-19H2/t20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	88	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro agonist binding affinity was determined by displacing the [3H]N-propylnorapomorphine ([3H]NPA) in rat striatal Dopamine receptor D2				Bioorg Med Chem Lett 3: 639-644 (1993) Article DOI: 10.1016/S0960-894X(01)81245-2 BindingDB Entry DOI: 10.7270/Q2222V75
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50055724 (1-[2-((S)-4-Phenyl-cyclohex-3-enyl)-ethyl]-4-pyrid...) Show SMILES C(CN1CCN(CC1)c1ccccn1)[C@H]1CCC(=CC1)c1ccccc1 |c:19| Show InChI InChI=1S/C23H29N3/c1-2-6-21(7-3-1)22-11-9-20(10-12-22)13-15-25-16-18-26(19-17-25)23-8-4-5-14-24-23/h1-8,11,14,20H,9-10,12-13,15-19H2/t20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	704	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from rat striatal Dopamine receptor D2				Bioorg Med Chem Lett 3: 639-644 (1993) Article DOI: 10.1016/S0960-894X(01)81245-2 BindingDB Entry DOI: 10.7270/Q2222V75
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50055724 (1-[2-((S)-4-Phenyl-cyclohex-3-enyl)-ethyl]-4-pyrid...) Show SMILES C(CN1CCN(CC1)c1ccccn1)[C@H]1CCC(=CC1)c1ccccc1 |c:19| Show InChI InChI=1S/C23H29N3/c1-2-6-21(7-3-1)22-11-9-20(10-12-22)13-15-25-16-18-26(19-17-25)23-8-4-5-14-24-23/h1-8,11,14,20H,9-10,12-13,15-19H2/t20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	412	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from rat striatal Dopamine receptor D2				Bioorg Med Chem Lett 3: 639-644 (1993) Article DOI: 10.1016/S0960-894X(01)81245-2 BindingDB Entry DOI: 10.7270/Q2222V75
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50055724 (1-[2-((S)-4-Phenyl-cyclohex-3-enyl)-ethyl]-4-pyrid...) Show SMILES C(CN1CCN(CC1)c1ccccn1)[C@H]1CCC(=CC1)c1ccccc1 |c:19| Show InChI InChI=1S/C23H29N3/c1-2-6-21(7-3-1)22-11-9-20(10-12-22)13-15-25-16-18-26(19-17-25)23-8-4-5-14-24-23/h1-8,11,14,20H,9-10,12-13,15-19H2/t20-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	>6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro agonist binding affinity was determined by displacing the [3H]N-propylnorapomorphine ([3H]NPA) in rat striatal Dopamine receptor D2				Bioorg Med Chem Lett 3: 639-644 (1993) Article DOI: 10.1016/S0960-894X(01)81245-2 BindingDB Entry DOI: 10.7270/Q2222V75
					More data for this Ligand-Target Pair