BDBM50056001 CHEMBL3325851
SMILES: C[C@@H](CF)OC(=O)N1CCC(CC1)Oc1ncnc(Oc2ccc(nc2C)S(C)(=O)=O)c1F
InChI Key: InChIKey=BKEOSKPDNQWDSX-LBPRGKRZSA-N
Data: 2 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
G-protein coupled receptor 119 (GPR119) (Homo sapiens (Human)) | BDBM50056001 (CHEMBL3325851) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 186 | n/a | n/a | n/a | n/a |
Arena Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Inhibition of human GPR119 activity by homogeneous time resolved fluorescence cyclase (cAMP) assay | Bioorg Med Chem Lett 24: 4332-5 (2014) Article DOI: 10.1016/j.bmcl.2014.06.071 BindingDB Entry DOI: 10.7270/Q2C82BZ7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucose-dependent insulinotropic receptor (Rattus norvegicus) | BDBM50056001 (CHEMBL3325851) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.68E+3 | n/a | n/a | n/a | n/a |
Arena Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Inhibition of rat GPR119 activity by homogeneous time resolved fluorescence cyclase (cAMP) assay | Bioorg Med Chem Lett 24: 4332-5 (2014) Article DOI: 10.1016/j.bmcl.2014.06.071 BindingDB Entry DOI: 10.7270/Q2C82BZ7 | |||||||||||
More data for this Ligand-Target Pair |