BDBM50056369 3-Amino-5,6-dimethyl-2-[3-(4-phenyl-piperazin-1-yl)-propylsulfanyl]-3H-thieno[2,3-d]pyrimidin-4-one::CHEMBL347179

SMILES: Cc1sc2nc(SCCCN3CCN(CC3)c3ccccc3)n(N)c(=O)c2c1C

InChI Key: InChIKey=UYFBHRYVNUJWBI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50056369   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50056369 (3-Amino-5,6-dimethyl-2-[3-(4-phenyl-piperazin-1-yl...) Show SMILES Cc1sc2nc(SCCCN3CCN(CC3)c3ccccc3)n(N)c(=O)c2c1C Show InChI InChI=1S/C21H27N5OS2/c1-15-16(2)29-19-18(15)20(27)26(22)21(23-19)28-14-6-9-24-10-12-25(13-11-24)17-7-4-3-5-8-17/h3-5,7-8H,6,9-14,22H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a	n/a
Università di Catania Curated by ChEMBL					Assay Description In vitro inhibitory concentration against radioligand [3H]-8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat hippocampal membrane.				J Med Chem 40: 574-85 (1997) Article DOI: 10.1021/jm950866t BindingDB Entry DOI: 10.7270/Q2K64H6C
					More data for this Ligand-Target Pair