BDBM50056372 2-{3-[4-(3-Chloro-phenyl)-piperazin-1-yl]-propylsulfanyl}-5,6-dimethyl-3H-thieno[2,3-d]pyrimidin-4-one::CHEMBL152223

SMILES: Cc1sc2nc(SCCCN3CCN(CC3)c3cccc(Cl)c3)[nH]c(=O)c2c1C

InChI Key: InChIKey=KZYXGRFDHNOBNQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50056372   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50056372 (2-{3-[4-(3-Chloro-phenyl)-piperazin-1-yl]-propylsu...) Show SMILES Cc1sc2nc(SCCCN3CCN(CC3)c3cccc(Cl)c3)[nH]c(=O)c2c1C Show InChI InChI=1S/C21H25ClN4OS2/c1-14-15(2)29-20-18(14)19(27)23-21(24-20)28-12-4-7-25-8-10-26(11-9-25)17-6-3-5-16(22)13-17/h3,5-6,13H,4,7-12H2,1-2H3,(H,23,24,27)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	986	n/a	n/a	n/a	n/a	n/a	n/a
Università di Catania Curated by ChEMBL					Assay Description In vitro inhibitory concentration against radioligand [3H]-8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat hippocampal membrane.				J Med Chem 40: 574-85 (1997) Article DOI: 10.1021/jm950866t BindingDB Entry DOI: 10.7270/Q2K64H6C
					More data for this Ligand-Target Pair