BDBM50056380 2-{3-[4-(2-Chloro-phenyl)-piperazin-1-yl]-propylsulfanyl}-5,6,7,8-tetrahydro-3H-benzo[4,5]thieno[2,3-d]pyrimidin-4-one::CHEMBL155601

SMILES: Clc1ccccc1N1CCN(CCCSc2nc3sc4CCCCc4c3c(=O)[nH]2)CC1

InChI Key: InChIKey=ZZEBFAYVGZLMBE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50056380   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50056380 (2-{3-[4-(2-Chloro-phenyl)-piperazin-1-yl]-propylsu...) Show SMILES Clc1ccccc1N1CCN(CCCSc2nc3sc4CCCCc4c3c(=O)[nH]2)CC1 Show InChI InChI=1S/C23H27ClN4OS2/c24-17-7-2-3-8-18(17)28-13-11-27(12-14-28)10-5-15-30-23-25-21(29)20-16-6-1-4-9-19(16)31-22(20)26-23/h2-3,7-8H,1,4-6,9-15H2,(H,25,26,29)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	943	n/a	n/a	n/a	n/a	n/a	n/a
Università di Catania Curated by ChEMBL					Assay Description In vitro inhibitory concentration against radioligand [3H]-8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat hippocampal membrane.				J Med Chem 40: 574-85 (1997) Article DOI: 10.1021/jm950866t BindingDB Entry DOI: 10.7270/Q2K64H6C
					More data for this Ligand-Target Pair