BDBM50056382 3-Amino-2-{3-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propylsulfanyl}-5,6,7,8-tetrahydro-3H-benzo[4,5]thieno[2,3-d]pyrimidin-4-one::CHEMBL155181

SMILES: COc1ccccc1N1CCN(CCCSc2nc3sc4CCCCc4c3c(=O)n2N)CC1

InChI Key: InChIKey=DZOIGSPMCOMTEW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50056382   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50056382 (3-Amino-2-{3-[4-(2-methoxy-phenyl)-piperazin-1-yl]...) Show SMILES COc1ccccc1N1CCN(CCCSc2nc3sc4CCCCc4c3c(=O)n2N)CC1 Show InChI InChI=1S/C24H31N5O2S2/c1-31-19-9-4-3-8-18(19)28-14-12-27(13-15-28)11-6-16-32-24-26-22-21(23(30)29(24)25)17-7-2-5-10-20(17)33-22/h3-4,8-9H,2,5-7,10-16,25H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
Università di Catania Curated by ChEMBL					Assay Description In vitro inhibitory concentration against radioligand [3H]-8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat hippocampal membrane.				J Med Chem 40: 574-85 (1997) Article DOI: 10.1021/jm950866t BindingDB Entry DOI: 10.7270/Q2K64H6C
					More data for this Ligand-Target Pair