BDBM50056385 2-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-propylsulfanyl}-6-phenyl-3H-thieno[2,3-d]pyrimidin-4-one::CHEMBL346143

SMILES: COc1ccccc1N1CCN(CCCSc2nc3sc(cc3c(=O)[nH]2)-c2ccccc2)CC1

InChI Key: InChIKey=FFCAMAURCVSEJQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50056385   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50056385 (2-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-propyls...) Show SMILES COc1ccccc1N1CCN(CCCSc2nc3sc(cc3c(=O)[nH]2)-c2ccccc2)CC1 Show InChI InChI=1S/C26H28N4O2S2/c1-32-22-11-6-5-10-21(22)30-15-13-29(14-16-30)12-7-17-33-26-27-24(31)20-18-23(34-25(20)28-26)19-8-3-2-4-9-19/h2-6,8-11,18H,7,12-17H2,1H3,(H,27,28,31)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	386	n/a	n/a	n/a	n/a	n/a	n/a
Università di Catania Curated by ChEMBL					Assay Description In vitro inhibitory concentration against radioligand [3H]-8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat hippocampal membrane.				J Med Chem 40: 574-85 (1997) Article DOI: 10.1021/jm950866t BindingDB Entry DOI: 10.7270/Q2K64H6C
					More data for this Ligand-Target Pair