BDBM50056406 4-Amino-5-chloro-2-methoxy-benzoic acid 2-(3-methyl-piperidin-1-yl)-ethyl ester::CHEMBL156349

SMILES: COc1cc(N)c(Cl)cc1C(=O)OCCN1CCCC(C)C1

InChI Key: InChIKey=WPZZZTYBCXELII-UHFFFAOYSA-N

Data: 2 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50056406   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
HTR4 (RAT)	BDBM50056406 (4-Amino-5-chloro-2-methoxy-benzoic acid 2-(3-methy...) Show SMILES COc1cc(N)c(Cl)cc1C(=O)OCCN1CCCC(C)C1 Show InChI InChI=1S/C16H23ClN2O3/c1-11-4-3-5-19(10-11)6-7-22-16(20)12-8-13(17)14(18)9-15(12)21-2/h8-9,11H,3-7,10,18H2,1-2H3	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.930	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS-BIOCIS Curated by ChEMBL					Assay Description Binding affinity towards 5-hydroxytryptamine 4 receptor was determined in rat striatal membranes using [3H]GR-113808 as radioligand				J Med Chem 40: 608-21 (1997) Article DOI: 10.1021/jm960320m BindingDB Entry DOI: 10.7270/Q2T72J36
					More data for this Ligand-Target Pair
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor (Rattus norvegicus-RAT)	BDBM50056406 (4-Amino-5-chloro-2-methoxy-benzoic acid 2-(3-methy...) Show SMILES COc1cc(N)c(Cl)cc1C(=O)OCCN1CCCC(C)C1 Show InChI InChI=1S/C16H23ClN2O3/c1-11-4-3-5-19(10-11)6-7-22-16(20)12-8-13(17)14(18)9-15(12)21-2/h8-9,11H,3-7,10,18H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS-BIOCIS Curated by ChEMBL					Assay Description Binding affinity was measured on 5-hydroxytryptamine 3 receptor using [3H]-BRL 43694 as radioligand in rat posterior cortex.				J Med Chem 40: 608-21 (1997) Article DOI: 10.1021/jm960320m BindingDB Entry DOI: 10.7270/Q2T72J36
					More data for this Ligand-Target Pair
HTR4 (GUINEA PIG)	BDBM50056406 (4-Amino-5-chloro-2-methoxy-benzoic acid 2-(3-methy...) Show SMILES COc1cc(N)c(Cl)cc1C(=O)OCCN1CCCC(C)C1 Show InChI InChI=1S/C16H23ClN2O3/c1-11-4-3-5-19(10-11)6-7-22-16(20)12-8-13(17)14(18)9-15(12)21-2/h8-9,11H,3-7,10,18H2,1-2H3	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	15	n/a	n/a	n/a	n/a
CNRS-BIOCIS Curated by ChEMBL					Assay Description 5-hydroxytryptamine 4 receptor agonist activity, concentration which gave 50% increase in the response to electrically-stimulated myenteric plexus an...				J Med Chem 40: 608-21 (1997) Article DOI: 10.1021/jm960320m BindingDB Entry DOI: 10.7270/Q2T72J36
					More data for this Ligand-Target Pair