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SMILES: Clc1ccc2c(NC(=O)Cc3ccccc3)c(-c3ccccc3)c(=O)[nH]c2c1

InChI Key: InChIKey=QVBHKNZTJPYVGT-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50056668   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50056668
PNG
(CHEMBL350411 | N-(7-Chloro-2-oxo-3-phenyl-1,2-dihy...)
Show SMILES Clc1ccc2c(NC(=O)Cc3ccccc3)c(-c3ccccc3)c(=O)[nH]c2c1
Show InChI InChI=1S/C23H17ClN2O2/c24-17-11-12-18-19(14-17)25-23(28)21(16-9-5-2-6-10-16)22(18)26-20(27)13-15-7-3-1-4-8-15/h1-12,14H,13H2,(H2,25,26,27,28)
PDB

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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]L-689,560 binding to glycine site on the N-methyl-D-aspartate (NMDA) glutamate receptor 1 from rat cortical membrane...

J Med Chem 40: 754-65 (1997)


Article DOI: 10.1021/jm9605492
BindingDB Entry DOI: 10.7270/Q2J67G1J
More data for this
Ligand-Target Pair