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SMILES: CCCCCn1c(N)nc2cc(C)ccc12

InChI Key: InChIKey=VXMUSEXRAMMOOD-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50056699   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Toll-like receptor 8


(Homo sapiens (Human))		BDBM50056699
PNG
(CHEMBL3326931)
Show SMILES CCCCCn1c(N)nc2cc(C)ccc12
Show InChI InChI=1S/C13H19N3/c1-3-4-5-8-16-12-7-6-10(2)9-11(12)15-13(16)14/h6-7,9H,3-5,8H2,1-2H3,(H2,14,15)
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Similars
Article
PubMed
n/an/an/an/a 4.57E+3n/an/an/an/a



University of Kansas

Curated by ChEMBL


Assay Description
Agonist activity at human TLR8 stably expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as NF-kappaB induction by liquid...

J Med Chem 57: 7325-41 (2014)


Article DOI: 10.1021/jm500701q
BindingDB Entry DOI: 10.7270/Q2JS9S3S
More data for this
Ligand-Target Pair