BindingDB logo
myBDB logout

null

SMILES: CC1=CC(=O)N(Nc2nc(nc3scc(-c4cccs4)c23)-c2cccs2)C1=O

InChI Key: InChIKey=VHFRQHKFRYOSFN-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50056852   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Receptor-type tyrosine-protein kinase FLT3


(Homo sapiens (Human))		BDBM50056852
PNG
(CHEMBL3290618)
Show SMILES CC1=CC(=O)N(Nc2nc(nc3scc(-c4cccs4)c23)-c2cccs2)C1=O |t:1|
Show InChI InChI=1S/C19H12N4O2S3/c1-10-8-14(24)23(19(10)25)22-17-15-11(12-4-2-6-26-12)9-28-18(15)21-16(20-17)13-5-3-7-27-13/h2-9H,1H3,(H,20,21,22)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 69n/an/an/an/an/an/a



Yonsei University

Curated by ChEMBL


Assay Description
Inhibition of human FLT3 using 10 uM ATP

Eur J Med Chem 85: 399-407 (2014)


Article DOI: 10.1016/j.ejmech.2014.08.001
BindingDB Entry DOI: 10.7270/Q2X35038
More data for this
Ligand-Target Pair