BDBM50057159 3-Benzo[1,3]dioxol-5-yl-4-benzyl-5-(4-benzyloxy-phenyl)-5-hydroxy-5H-furan-2-one::CHEMBL11341

SMILES: OC1(OC(=O)C(=C1Cc1ccccc1)c1ccc2OCOc2c1)c1ccc(OCc2ccccc2)cc1

InChI Key: InChIKey=JPQNTLPMEWVANT-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50057159   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelin-1 receptor (Homo sapiens (Human))	BDBM50057159 (3-Benzo[1,3]dioxol-5-yl-4-benzyl-5-(4-benzyloxy-ph...) Show SMILES OC1(OC(=O)C(=C1Cc1ccccc1)c1ccc2OCOc2c1)c1ccc(OCc2ccccc2)cc1 |c:5| Show InChI InChI=1S/C31H24O6/c32-30-29(23-11-16-27-28(18-23)36-20-35-27)26(17-21-7-3-1-4-8-21)31(33,37-30)24-12-14-25(15-13-24)34-19-22-9-5-2-6-10-22/h1-16,18,33H,17,19-20H2	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	950	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Binding affinity against human cloned endothelin A receptor expressed in LTK-cells				J Med Chem 40: 1063-74 (1997) Article DOI: 10.1021/jm9606507 BindingDB Entry DOI: 10.7270/Q27P8XG5
					More data for this Ligand-Target Pair
EDNRB (Homo sapiens (Human))	BDBM50057159 (3-Benzo[1,3]dioxol-5-yl-4-benzyl-5-(4-benzyloxy-ph...) Show SMILES OC1(OC(=O)C(=C1Cc1ccccc1)c1ccc2OCOc2c1)c1ccc(OCc2ccccc2)cc1 |c:5| Show InChI InChI=1S/C31H24O6/c32-30-29(23-11-16-27-28(18-23)36-20-35-27)26(17-21-7-3-1-4-8-21)31(33,37-30)24-12-14-25(15-13-24)34-19-22-9-5-2-6-10-22/h1-16,18,33H,17,19-20H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Binding affinity against human cloned Endothelin B receptor expressed in CHO-K1 cells				J Med Chem 40: 1063-74 (1997) Article DOI: 10.1021/jm9606507 BindingDB Entry DOI: 10.7270/Q27P8XG5
					More data for this Ligand-Target Pair