BDBM50057205 4-Benzyl-3-(3,5-dimethoxy-phenyl)-5-hydroxy-5-(4-methoxy-phenyl)-5H-furan-2-one::CHEMBL268754

SMILES: COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1ccccc1)c1cc(OC)cc(OC)c1

InChI Key: InChIKey=ZOSIIZNBOBYSGU-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50057205   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelin-1 receptor (Homo sapiens (Human))	BDBM50057205 (4-Benzyl-3-(3,5-dimethoxy-phenyl)-5-hydroxy-5-(4-m...) Show SMILES COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1ccccc1)c1cc(OC)cc(OC)c1 |c:14| Show InChI InChI=1S/C26H24O6/c1-29-20-11-9-19(10-12-20)26(28)23(13-17-7-5-4-6-8-17)24(25(27)32-26)18-14-21(30-2)16-22(15-18)31-3/h4-12,14-16,28H,13H2,1-3H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Binding affinity against human cloned endothelin A receptor expressed in LTK-cells				J Med Chem 40: 1063-74 (1997) Article DOI: 10.1021/jm9606507 BindingDB Entry DOI: 10.7270/Q27P8XG5
					More data for this Ligand-Target Pair
EDNRB (Homo sapiens (Human))	BDBM50057205 (4-Benzyl-3-(3,5-dimethoxy-phenyl)-5-hydroxy-5-(4-m...) Show SMILES COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1ccccc1)c1cc(OC)cc(OC)c1 |c:14| Show InChI InChI=1S/C26H24O6/c1-29-20-11-9-19(10-12-20)26(28)23(13-17-7-5-4-6-8-17)24(25(27)32-26)18-14-21(30-2)16-22(15-18)31-3/h4-12,14-16,28H,13H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Binding affinity against human cloned Endothelin B receptor expressed in CHO-K1 cells				J Med Chem 40: 1063-74 (1997) Article DOI: 10.1021/jm9606507 BindingDB Entry DOI: 10.7270/Q27P8XG5
					More data for this Ligand-Target Pair