null

SMILES: COc1ccc(OC)c(Sc2ccc3ncc(-c4cnn(C)c4)n3n2)c1

InChI Key: InChIKey=JCYIJNNJXPQREM-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50057226   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50057226 (CHEMBL3326147) Show SMILES COc1ccc(OC)c(Sc2ccc3ncc(-c4cnn(C)c4)n3n2)c1 Show InChI InChI=1S/C18H17N5O2S/c1-22-11-12(9-20-22)14-10-19-17-6-7-18(21-23(14)17)26-16-8-13(24-2)4-5-15(16)25-3/h4-11H,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of phosphorylation at S935 residue of wild-type full-length LRRK2 kinase (unknown origin) expressed in HEK 293 cells after 90 mins by ELIS...				Bioorg Med Chem Lett 24: 4132-40 (2014) Article DOI: 10.1016/j.bmcl.2014.07.052 BindingDB Entry DOI: 10.7270/Q2D50PMD
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50057226 (CHEMBL3326147) Show SMILES COc1ccc(OC)c(Sc2ccc3ncc(-c4cnn(C)c4)n3n2)c1 Show InChI InChI=1S/C18H17N5O2S/c1-22-11-12(9-20-22)14-10-19-17-6-7-18(21-23(14)17)26-16-8-13(24-2)4-5-15(16)25-3/h4-11H,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	69	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of GST-tagged truncated LRRK2 (unknown origin) using fluorescein-labeled peptide LRRKtide as substrate by LANTHA screen assay in presence ...				Bioorg Med Chem Lett 24: 4132-40 (2014) Article DOI: 10.1016/j.bmcl.2014.07.052 BindingDB Entry DOI: 10.7270/Q2D50PMD
					More data for this Ligand-Target Pair