null

SMILES: NC(=O)c1nn(c(c1Cl)-c1ccc(Cl)cc1)-c1ccc(cc1)S(N)(=O)=O

InChI Key: InChIKey=NMOJAXQDSULNMZ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50057587   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50057587 (4-Chloro-5-(4-chloro-phenyl)-1-(4-sulfamoyl-phenyl...) Show SMILES NC(=O)c1nn(c(c1Cl)-c1ccc(Cl)cc1)-c1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C16H12Cl2N4O3S/c17-10-3-1-9(2-4-10)15-13(18)14(16(19)23)21-22(15)11-5-7-12(8-6-11)26(20,24)25/h1-8H,(H2,19,23)(H2,20,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Searle Research and Development Curated by ChEMBL					Assay Description In vitro inhibitory concentration required to block recombinant human prostaglandin G/H synthase 1 (COX-1)				J Med Chem 40: 1347-65 (1997) Article DOI: 10.1021/jm960803q BindingDB Entry DOI: 10.7270/Q2Z89BHB
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50057587 (4-Chloro-5-(4-chloro-phenyl)-1-(4-sulfamoyl-phenyl...) Show SMILES NC(=O)c1nn(c(c1Cl)-c1ccc(Cl)cc1)-c1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C16H12Cl2N4O3S/c17-10-3-1-9(2-4-10)15-13(18)14(16(19)23)21-22(15)11-5-7-12(8-6-11)26(20,24)25/h1-8H,(H2,19,23)(H2,20,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.09E+3	n/a	n/a	n/a	n/a	n/a	n/a
Searle Research and Development Curated by ChEMBL					Assay Description In vitro inhibitory concentration required to block human recombinant prostaglandin G/H synthase 2 (COX-2)				J Med Chem 40: 1347-65 (1997) Article DOI: 10.1021/jm960803q BindingDB Entry DOI: 10.7270/Q2Z89BHB
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Mus musculus (Mouse))	BDBM50057587 (4-Chloro-5-(4-chloro-phenyl)-1-(4-sulfamoyl-phenyl...) Show SMILES NC(=O)c1nn(c(c1Cl)-c1ccc(Cl)cc1)-c1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C16H12Cl2N4O3S/c17-10-3-1-9(2-4-10)15-13(18)14(16(19)23)21-22(15)11-5-7-12(8-6-11)26(20,24)25/h1-8H,(H2,19,23)(H2,20,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibitory activity against prostaglandin G/H synthase 2 (COX-2)				J Med Chem 45: 4816-27 (2002) BindingDB Entry DOI: 10.7270/Q2XP764T
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50057587 (4-Chloro-5-(4-chloro-phenyl)-1-(4-sulfamoyl-phenyl...) Show SMILES NC(=O)c1nn(c(c1Cl)-c1ccc(Cl)cc1)-c1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C16H12Cl2N4O3S/c17-10-3-1-9(2-4-10)15-13(18)14(16(19)23)21-22(15)11-5-7-12(8-6-11)26(20,24)25/h1-8H,(H2,19,23)(H2,20,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Lille 2 Curated by ChEMBL					Assay Description Inhibition of human Prostaglandin G/H synthase 2				J Med Chem 44: 3223-30 (2001) BindingDB Entry DOI: 10.7270/Q2736S4D
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50057587 (4-Chloro-5-(4-chloro-phenyl)-1-(4-sulfamoyl-phenyl...) Show SMILES NC(=O)c1nn(c(c1Cl)-c1ccc(Cl)cc1)-c1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C16H12Cl2N4O3S/c17-10-3-1-9(2-4-10)15-13(18)14(16(19)23)21-22(15)11-5-7-12(8-6-11)26(20,24)25/h1-8H,(H2,19,23)(H2,20,24,25)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	8.71E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibitory activity against prostaglandin G/H synthase 1 (COX-1)				J Med Chem 45: 4816-27 (2002) BindingDB Entry DOI: 10.7270/Q2XP764T
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50057587 (4-Chloro-5-(4-chloro-phenyl)-1-(4-sulfamoyl-phenyl...) Show SMILES NC(=O)c1nn(c(c1Cl)-c1ccc(Cl)cc1)-c1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C16H12Cl2N4O3S/c17-10-3-1-9(2-4-10)15-13(18)14(16(19)23)21-22(15)11-5-7-12(8-6-11)26(20,24)25/h1-8H,(H2,19,23)(H2,20,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.09E+3	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Inhibitory concentration against human prostaglandin G/H synthase 2 at 25 degrees.				Bioorg Med Chem Lett 12: 267-70 (2002) BindingDB Entry DOI: 10.7270/Q2Q23ZJQ
					More data for this Ligand-Target Pair