BDBM50057682 7-(4-Aminomethyl-phenyl)-heptanoic acid {(S)-1-[(S)-5-amino-1-(2-cyclohexyl-ethylcarbamoyl)-pentylcarbamoyl]-2-hydroxy-ethyl}-amide::CHEMBL33856
SMILES: NCCCC[C@H](NC(=O)[C@H](CO)NC(=O)CCCCCCc1ccc(CN)cc1)C(=O)NCCC1CCCCC1
InChI Key: InChIKey=JZBSLOMXRHIHDB-NSOVKSMOSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Myristoyl-CoA:protein N-myristoyltransferase (Nmt) (Candida albicans (Yeast)) | BDBM50057682 (7-(4-Aminomethyl-phenyl)-heptanoic acid {(S)-1-[(S...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 340 | n/a | n/a | n/a | n/a | n/a | n/a |
G. D. Searle Research and Development Curated by ChEMBL | Assay Description Inhibitory activity against N-myristoyltransferase (NMT) of candida albicans | J Med Chem 40: 1422-38 (1997) Article DOI: 10.1021/jm9608671 BindingDB Entry DOI: 10.7270/Q2GB24Q7 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) |