BDBM50058034 CHEMBL3330788

SMILES: Cl.NCCNc1c2C(=O)c3ccccc3C(=O)c2c(NCCNC(N)=N)c2ccsc12

InChI Key: InChIKey=BEQIJPCKRVYXPO-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50058034   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50058034 (CHEMBL3330788) Show SMILES Cl.NCCNc1c2C(=O)c3ccccc3C(=O)c2c(NCCNC(N)=N)c2ccsc12 Show InChI InChI=1S/C21H22N6O2S.ClH/c22-6-7-25-17-15-14(18(28)11-3-1-2-4-12(11)19(15)29)16(13-5-10-30-20(13)17)26-8-9-27-21(23)24;/h1-5,10,25-26H,6-9,22H2,(H4,23,24,27);1H	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Russian Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human telomerase transfected in human HEK293T cells assessed as DNA extension using 5'-d(AATCCGTCGAGCAGAGTT)-3' substrate by Real-time ...				Eur J Med Chem 85: 605-14 (2014) Article DOI: 10.1016/j.ejmech.2014.08.030 BindingDB Entry DOI: 10.7270/Q2FX7C4Z
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50058034 (CHEMBL3330788) Show SMILES Cl.NCCNc1c2C(=O)c3ccccc3C(=O)c2c(NCCNC(N)=N)c2ccsc12 Show InChI InChI=1S/C21H22N6O2S.ClH/c22-6-7-25-17-15-14(18(28)11-3-1-2-4-12(11)19(15)29)16(13-5-10-30-20(13)17)26-8-9-27-21(23)24;/h1-5,10,25-26H,6-9,22H2,(H4,23,24,27);1H	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
Russian Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human telomerase transfected in human HEK293T cells assessed as DNA extension using 5'-d(AATCCGTCGAGCAGAGTT)-3' substrate				Eur J Med Chem 85: 605-14 (2014) Article DOI: 10.1016/j.ejmech.2014.08.030 BindingDB Entry DOI: 10.7270/Q2FX7C4Z
					More data for this Ligand-Target Pair