BDBM50058182 (4-Amino-5-chloro-2-methoxy-phenyl)-carbamic acid 2-diethylamino-ethyl ester::CHEMBL49072

SMILES: CCN(CC)CCOC(=O)Nc1cc(Cl)c(N)cc1OC

InChI Key: InChIKey=XYNDSBRZROCADQ-UHFFFAOYSA-N

Data: 1 KI  1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50058182   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
HTR4 (RAT)	BDBM50058182 ((4-Amino-5-chloro-2-methoxy-phenyl)-carbamic acid ...) Show SMILES CCN(CC)CCOC(=O)Nc1cc(Cl)c(N)cc1OC Show InChI InChI=1S/C14H22ClN3O3/c1-4-18(5-2)6-7-21-14(19)17-12-8-10(15)11(16)9-13(12)20-3/h8-9H,4-7,16H2,1-3H3,(H,17,19)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS-BIOCIS Curated by ChEMBL					Assay Description Binding affinity (Ki+/-SEM) against 5-hydroxytryptamine 4 receptor from cheng Prusoff equation by using [3H]-GR 113808 in rat striatum				J Med Chem 40: 1755-61 (1997) Article DOI: 10.1021/jm960853v BindingDB Entry DOI: 10.7270/Q2NS0T0C
					More data for this Ligand-Target Pair
HTR4 (GUINEA PIG)	BDBM50058182 ((4-Amino-5-chloro-2-methoxy-phenyl)-carbamic acid ...) Show SMILES CCN(CC)CCOC(=O)Nc1cc(Cl)c(N)cc1OC Show InChI InChI=1S/C14H22ClN3O3/c1-4-18(5-2)6-7-21-14(19)17-12-8-10(15)11(16)9-13(12)20-3/h8-9H,4-7,16H2,1-3H3,(H,17,19)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a
CNRS-BIOCIS Curated by ChEMBL					Assay Description concentration which gave a 50% increase in the response to electrical stimulation against 5-hydroxytryptamine 4 receptor in the guinea pig ileum. Act...				J Med Chem 40: 1755-61 (1997) Article DOI: 10.1021/jm960853v BindingDB Entry DOI: 10.7270/Q2NS0T0C
					More data for this Ligand-Target Pair
HTR4 (GUINEA PIG)	BDBM50058182 ((4-Amino-5-chloro-2-methoxy-phenyl)-carbamic acid ...) Show SMILES CCN(CC)CCOC(=O)Nc1cc(Cl)c(N)cc1OC Show InChI InChI=1S/C14H22ClN3O3/c1-4-18(5-2)6-7-21-14(19)17-12-8-10(15)11(16)9-13(12)20-3/h8-9H,4-7,16H2,1-3H3,(H,17,19)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
CNRS-BIOCIS Curated by ChEMBL					Assay Description The antagonist activity was calculated as the concentration which produced a 50% reduction against 5-hydroxytryptamine 4 receptor in guinea pig ileum...				J Med Chem 40: 1755-61 (1997) Article DOI: 10.1021/jm960853v BindingDB Entry DOI: 10.7270/Q2NS0T0C
					More data for this Ligand-Target Pair