BDBM50058241 CHEMBL53433::{[2-(4-Chloro-phenyl)-quinoline-4-carbonyl]-amino}-phenyl-acetic acid methyl ester

SMILES: COC(=O)C(NC(=O)c1cc(nc2ccccc12)-c1ccc(Cl)cc1)c1ccccc1

InChI Key: InChIKey=ZSDYIUVQNWIAIS-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50058241   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50058241 (CHEMBL53433 | {[2-(4-Chloro-phenyl)-quinoline-4-ca...) Show SMILES COC(=O)C(NC(=O)c1cc(nc2ccccc12)-c1ccc(Cl)cc1)c1ccccc1 Show InChI InChI=1S/C25H19ClN2O3/c1-31-25(30)23(17-7-3-2-4-8-17)28-24(29)20-15-22(16-11-13-18(26)14-12-16)27-21-10-6-5-9-19(20)21/h2-15,23H,1H3,(H,28,29)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	820	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham S.p.A. Milano Curated by ChEMBL					Assay Description Inhibition of [125I]-MePhe7-Neurokinin B (NKB) binding in human Tachykinin receptor 3 of chinese hamster ovary (hNK-3-CHO) cell membranes.				J Med Chem 40: 1794-807 (1997) Article DOI: 10.1021/jm960818o BindingDB Entry DOI: 10.7270/Q24T6HHB
					More data for this Ligand-Target Pair