BDBM50058290 (2R,3S)-8-Benzyl-3-[bis-(4-fluoro-phenyl)-methoxy]-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester::CHEMBL55174

SMILES: COC(=O)[C@@H]1C2CCC(C[C@@H]1OC(c1ccc(F)cc1)c1ccc(F)cc1)N2Cc1ccccc1

InChI Key: InChIKey=DVAFIFWOFNIVEV-VPMXTDFASA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50058290   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dopamine transporter (Macaca fascicularis)	BDBM50058290 ((2R,3S)-8-Benzyl-3-[bis-(4-fluoro-phenyl)-methoxy]...) Show SMILES COC(=O)[C@@H]1C2CCC(C[C@@H]1OC(c1ccc(F)cc1)c1ccc(F)cc1)N2Cc1ccccc1 |TLB:11:10:27:6.7,28:27:4.10.9:6.7,THB:2:4:27:6.7| Show InChI InChI=1S/C29H29F2NO3/c1-34-29(33)27-25-16-15-24(32(25)18-19-5-3-2-4-6-19)17-26(27)35-28(20-7-11-22(30)12-8-20)21-9-13-23(31)14-10-21/h2-14,24-28H,15-18H2,1H3/t24?,25?,26-,27+/m0/s1	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	223	n/a	n/a	n/a	n/a	n/a	n/a
Organix Inc. Curated by ChEMBL					Assay Description Inhibition of [3H]WIN35,428 binding to dopamine transporter using of Cynomolgus monkey caudate-putamen				J Med Chem 40: 1835-44 (1997) Article DOI: 10.1021/jm960868t BindingDB Entry DOI: 10.7270/Q2125RSX
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50058290 ((2R,3S)-8-Benzyl-3-[bis-(4-fluoro-phenyl)-methoxy]...) Show SMILES COC(=O)[C@@H]1C2CCC(C[C@@H]1OC(c1ccc(F)cc1)c1ccc(F)cc1)N2Cc1ccccc1 |TLB:11:10:27:6.7,28:27:4.10.9:6.7,THB:2:4:27:6.7| Show InChI InChI=1S/C29H29F2NO3/c1-34-29(33)27-25-16-15-24(32(25)18-19-5-3-2-4-6-19)17-26(27)35-28(20-7-11-22(30)12-8-20)21-9-13-23(31)14-10-21/h2-14,24-28H,15-18H2,1H3/t24?,25?,26-,27+/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.97E+3	n/a	n/a	n/a	n/a	n/a	n/a
Organix Inc. Curated by ChEMBL					Assay Description Inhibition of [3H]- citalopram binding to serotonin transporter of Cynomolgus monkey caudate-putamen				J Med Chem 40: 1835-44 (1997) Article DOI: 10.1021/jm960868t BindingDB Entry DOI: 10.7270/Q2125RSX
					More data for this Ligand-Target Pair