BDBM50058592 CHEMBL291993::N-hydroxy-N-[3-(3-phenoxyphenyl)prop-2-ynyl]urea

SMILES: NC(=O)N(O)CC#Cc1cccc(Oc2ccccc2)c1

InChI Key: InChIKey=NONPBBRHJJOOHA-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50058592   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50058592 (CHEMBL291993 | N-hydroxy-N-[3-(3-phenoxyphenyl)pro...) Show SMILES NC(=O)N(O)CC#Cc1cccc(Oc2ccccc2)c1 Show InChI InChI=1S/C16H14N2O3/c17-16(19)18(20)11-5-7-13-6-4-10-15(12-13)21-14-8-2-1-3-9-14/h1-4,6,8-10,12,20H,11H2,(H2,17,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of 5-lipoxygenase on rat basophil leukemia cell line lysate (RBL-1 2H3 subline) by measuring 5-HETE production				J Med Chem 40: 1955-68 (1997) Article DOI: 10.1021/jm9700474 BindingDB Entry DOI: 10.7270/Q2NV9JWT
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Homo sapiens (Human))	BDBM50058592 (CHEMBL291993 | N-hydroxy-N-[3-(3-phenoxyphenyl)pro...) Show SMILES NC(=O)N(O)CC#Cc1cccc(Oc2ccccc2)c1 Show InChI InChI=1S/C16H14N2O3/c17-16(19)18(20)11-5-7-13-6-4-10-15(12-13)21-14-8-2-1-3-9-14/h1-4,6,8-10,12,20H,11H2,(H2,17,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of 5-lipoxygenase (5-LO) measured as LTB4 production in human whole blood stimulated with calcium ionophore (A23187).				J Med Chem 40: 1955-68 (1997) Article DOI: 10.1021/jm9700474 BindingDB Entry DOI: 10.7270/Q2NV9JWT
					More data for this Ligand-Target Pair