null

SMILES: Cc1ccc(cc1C)N1CC(=O)N(C1=O)S(=O)(=O)c1ccc(Cl)cc1

InChI Key: InChIKey=FZZIIAUJWUWYCF-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50058969   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cathepsin G (Homo sapiens (Human))	BDBM50058969 (3-(4-Chloro-benzenesulfonyl)-1-(3,4-dimethyl-pheny...) Show SMILES Cc1ccc(cc1C)N1CC(=O)N(C1=O)S(=O)(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C17H15ClN2O4S/c1-11-3-6-14(9-12(11)2)19-10-16(21)20(17(19)22)25(23,24)15-7-4-13(18)5-8-15/h3-9H,10H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Suntory Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against human neutrophil cathepsin G.				J Med Chem 40: 2156-63 (1997) Article DOI: 10.1021/jm960793t BindingDB Entry DOI: 10.7270/Q2QJ7GDG
					More data for this Ligand-Target Pair
Chymase (Homo sapiens (Human))	BDBM50058969 (3-(4-Chloro-benzenesulfonyl)-1-(3,4-dimethyl-pheny...) Show SMILES Cc1ccc(cc1C)N1CC(=O)N(C1=O)S(=O)(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C17H15ClN2O4S/c1-11-3-6-14(9-12(11)2)19-10-16(21)20(17(19)22)25(23,24)15-7-4-13(18)5-8-15/h3-9H,10H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Suntory Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against human heart chymase in vitro.				J Med Chem 40: 2156-63 (1997) Article DOI: 10.1021/jm960793t BindingDB Entry DOI: 10.7270/Q2QJ7GDG
					More data for this Ligand-Target Pair
Chymotrypsinogen A (Bos taurus (bovine))	BDBM50058969 (3-(4-Chloro-benzenesulfonyl)-1-(3,4-dimethyl-pheny...) Show SMILES Cc1ccc(cc1C)N1CC(=O)N(C1=O)S(=O)(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C17H15ClN2O4S/c1-11-3-6-14(9-12(11)2)19-10-16(21)20(17(19)22)25(23,24)15-7-4-13(18)5-8-15/h3-9H,10H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Suntory Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against bovine pancreas alpha-chymotrypsin in vitro				J Med Chem 40: 2156-63 (1997) Article DOI: 10.1021/jm960793t BindingDB Entry DOI: 10.7270/Q2QJ7GDG
					More data for this Ligand-Target Pair