BDBM50058979 3-(2,5-Dioxo-3-phenyl-imidazolidine-1-sulfonyl)-benzoic acid::CHEMBL66504

SMILES: OC(=O)c1cccc(c1)S(=O)(=O)N1C(=O)CN(C1=O)c1ccccc1

InChI Key: InChIKey=AEVPIESDIOSSSM-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50058979   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Chymase (Homo sapiens (Human))	BDBM50058979 (3-(2,5-Dioxo-3-phenyl-imidazolidine-1-sulfonyl)-be...) Show SMILES OC(=O)c1cccc(c1)S(=O)(=O)N1C(=O)CN(C1=O)c1ccccc1 Show InChI InChI=1S/C16H12N2O6S/c19-14-10-17(12-6-2-1-3-7-12)16(22)18(14)25(23,24)13-8-4-5-11(9-13)15(20)21/h1-9H,10H2,(H,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	860	n/a	n/a	n/a	n/a	n/a	n/a
Suntory Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against human heart chymase in vitro.				J Med Chem 40: 2156-63 (1997) Article DOI: 10.1021/jm960793t BindingDB Entry DOI: 10.7270/Q2QJ7GDG
					More data for this Ligand-Target Pair
Chymotrypsinogen A (Bos taurus (bovine))	BDBM50058979 (3-(2,5-Dioxo-3-phenyl-imidazolidine-1-sulfonyl)-be...) Show SMILES OC(=O)c1cccc(c1)S(=O)(=O)N1C(=O)CN(C1=O)c1ccccc1 Show InChI InChI=1S/C16H12N2O6S/c19-14-10-17(12-6-2-1-3-7-12)16(22)18(14)25(23,24)13-8-4-5-11(9-13)15(20)21/h1-9H,10H2,(H,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Suntory Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against bovine pancreas alpha-chymotrypsin in vitro				J Med Chem 40: 2156-63 (1997) Article DOI: 10.1021/jm960793t BindingDB Entry DOI: 10.7270/Q2QJ7GDG
					More data for this Ligand-Target Pair
Cathepsin G (Homo sapiens (Human))	BDBM50058979 (3-(2,5-Dioxo-3-phenyl-imidazolidine-1-sulfonyl)-be...) Show SMILES OC(=O)c1cccc(c1)S(=O)(=O)N1C(=O)CN(C1=O)c1ccccc1 Show InChI InChI=1S/C16H12N2O6S/c19-14-10-17(12-6-2-1-3-7-12)16(22)18(14)25(23,24)13-8-4-5-11(9-13)15(20)21/h1-9H,10H2,(H,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Suntory Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against human neutrophil cathepsin G.				J Med Chem 40: 2156-63 (1997) Article DOI: 10.1021/jm960793t BindingDB Entry DOI: 10.7270/Q2QJ7GDG
					More data for this Ligand-Target Pair