BDBM50058995 3-[4-(4-Methyl-piperazine-1-carbonyl)-benzenesulfonyl]-1-phenyl-imidazolidine-2,4-dione::CHEMBL70061

SMILES: CN1CCN(CC1)C(=O)c1ccc(cc1)S(=O)(=O)N1C(=O)CN(C1=O)c1ccccc1

InChI Key: InChIKey=UCEDOYMXRBWHTD-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50058995   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Chymotrypsinogen A (Bos taurus (bovine))	BDBM50058995 (3-[4-(4-Methyl-piperazine-1-carbonyl)-benzenesulfo...) Show SMILES CN1CCN(CC1)C(=O)c1ccc(cc1)S(=O)(=O)N1C(=O)CN(C1=O)c1ccccc1 Show InChI InChI=1S/C21H22N4O5S/c1-22-11-13-23(14-12-22)20(27)16-7-9-18(10-8-16)31(29,30)25-19(26)15-24(21(25)28)17-5-3-2-4-6-17/h2-10H,11-15H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Suntory Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against bovine pancreas alpha-chymotrypsin in vitro				J Med Chem 40: 2156-63 (1997) Article DOI: 10.1021/jm960793t BindingDB Entry DOI: 10.7270/Q2QJ7GDG
					More data for this Ligand-Target Pair
Chymase (Homo sapiens (Human))	BDBM50058995 (3-[4-(4-Methyl-piperazine-1-carbonyl)-benzenesulfo...) Show SMILES CN1CCN(CC1)C(=O)c1ccc(cc1)S(=O)(=O)N1C(=O)CN(C1=O)c1ccccc1 Show InChI InChI=1S/C21H22N4O5S/c1-22-11-13-23(14-12-22)20(27)16-7-9-18(10-8-16)31(29,30)25-19(26)15-24(21(25)28)17-5-3-2-4-6-17/h2-10H,11-15H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Suntory Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against human heart chymase in vitro.				J Med Chem 40: 2156-63 (1997) Article DOI: 10.1021/jm960793t BindingDB Entry DOI: 10.7270/Q2QJ7GDG
					More data for this Ligand-Target Pair
Cathepsin G (Homo sapiens (Human))	BDBM50058995 (3-[4-(4-Methyl-piperazine-1-carbonyl)-benzenesulfo...) Show SMILES CN1CCN(CC1)C(=O)c1ccc(cc1)S(=O)(=O)N1C(=O)CN(C1=O)c1ccccc1 Show InChI InChI=1S/C21H22N4O5S/c1-22-11-13-23(14-12-22)20(27)16-7-9-18(10-8-16)31(29,30)25-19(26)15-24(21(25)28)17-5-3-2-4-6-17/h2-10H,11-15H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Suntory Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against human neutrophil cathepsin G.				J Med Chem 40: 2156-63 (1997) Article DOI: 10.1021/jm960793t BindingDB Entry DOI: 10.7270/Q2QJ7GDG
					More data for this Ligand-Target Pair