null

SMILES: Oc1cn(-c2ccccc2)c(=O)n1C(=O)c1ccc(Cl)cc1

InChI Key: InChIKey=DJVODPFHGRCVFE-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50059013   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cathepsin G (Homo sapiens (Human))	BDBM50059013 (3-(4-Chloro-benzoyl)-1-phenyl-imidazolidine-2,4-di...) Show SMILES Oc1cn(-c2ccccc2)c(=O)n1C(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C16H11ClN2O3/c17-12-8-6-11(7-9-12)15(21)19-14(20)10-18(16(19)22)13-4-2-1-3-5-13/h1-10,20H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Suntory Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against human neutrophil cathepsin G.				J Med Chem 40: 2156-63 (1997) Article DOI: 10.1021/jm960793t BindingDB Entry DOI: 10.7270/Q2QJ7GDG
					More data for this Ligand-Target Pair
Chymase (Homo sapiens (Human))	BDBM50059013 (3-(4-Chloro-benzoyl)-1-phenyl-imidazolidine-2,4-di...) Show SMILES Oc1cn(-c2ccccc2)c(=O)n1C(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C16H11ClN2O3/c17-12-8-6-11(7-9-12)15(21)19-14(20)10-18(16(19)22)13-4-2-1-3-5-13/h1-10,20H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Suntory Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against human heart chymase in vitro.				J Med Chem 40: 2156-63 (1997) Article DOI: 10.1021/jm960793t BindingDB Entry DOI: 10.7270/Q2QJ7GDG
					More data for this Ligand-Target Pair
Chymotrypsinogen A (Bos taurus (bovine))	BDBM50059013 (3-(4-Chloro-benzoyl)-1-phenyl-imidazolidine-2,4-di...) Show SMILES Oc1cn(-c2ccccc2)c(=O)n1C(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C16H11ClN2O3/c17-12-8-6-11(7-9-12)15(21)19-14(20)10-18(16(19)22)13-4-2-1-3-5-13/h1-10,20H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
Suntory Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against bovine pancreas alpha-chymotrypsin in vitro				J Med Chem 40: 2156-63 (1997) Article DOI: 10.1021/jm960793t BindingDB Entry DOI: 10.7270/Q2QJ7GDG
					More data for this Ligand-Target Pair