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SMILES: COC(=O)c1ccccc1Nc1nc(Nc2ccc(CNC(=O)OC=C)cc2)n2ccnc2n1

InChI Key: InChIKey=XZACQGDBORLPQD-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50059149   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Focal adhesion kinase 1


(Homo sapiens (Human))		BDBM50059149
PNG
(CHEMBL3393279)
Show SMILES COC(=O)c1ccccc1Nc1nc(Nc2ccc(CNC(=O)OC=C)cc2)n2ccnc2n1
Show InChI InChI=1S/C23H21N7O4/c1-3-34-23(32)25-14-15-8-10-16(11-9-15)26-22-29-20(28-21-24-12-13-30(21)22)27-18-7-5-4-6-17(18)19(31)33-2/h3-13H,1,14H2,2H3,(H,25,32)(H2,24,26,27,28,29)
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Article
PubMed
n/an/a 1.05E+3n/an/an/an/an/an/a



Universit£ Paris Descartes

Curated by ChEMBL


Assay Description
Inhibition of FAK (unknown origin) using ULight-poly GT as substrate after 1.6 hrs by TR-FRET assay

J Med Chem 58: 237-51 (2015)


Article DOI: 10.1021/jm500784e
BindingDB Entry DOI: 10.7270/Q2B27WZC
More data for this
Ligand-Target Pair