BindingDB logo
myBDB logout

null

SMILES: Cc1nc(Nc2cc(ccn2)C(F)(F)F)cc(n1)C1CCCNC1

InChI Key: InChIKey=SOEURGICWVACEJ-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50059244   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase kinase kinase 12


(Homo sapiens (Human))		BDBM50059244
PNG
(CHEMBL3393319)
Show SMILES Cc1nc(Nc2cc(ccn2)C(F)(F)F)cc(n1)C1CCCNC1
Show InChI InChI=1S/C16H18F3N5/c1-10-22-13(11-3-2-5-20-9-11)8-15(23-10)24-14-7-12(4-6-21-14)16(17,18)19/h4,6-8,11,20H,2-3,5,9H2,1H3,(H,21,22,23,24)
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 725n/an/an/an/an/an/an/an/a



Genentech

Curated by ChEMBL


Assay Description
Inhibition of DLK (unknown origin)

J Med Chem 58: 401-18 (2015)


Article DOI: 10.1021/jm5013984
BindingDB Entry DOI: 10.7270/Q22J6DJ5
More data for this
Ligand-Target Pair