BDBM50059475 2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-hexahydro-pyrrolo[1,2-c]imidazole::CHEMBL315472

SMILES: COc1ccccc1N1CCN(CCCCN2CC3CCCN3C2)CC1

InChI Key: InChIKey=VHPARWYQZXICHJ-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50059475   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50059475 (2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...) Show SMILES COc1ccccc1N1CCN(CCCCN2CC3CCCN3C2)CC1 Show InChI InChI=1S/C21H34N4O/c1-26-21-9-3-2-8-20(21)24-15-13-22(14-16-24)10-4-5-11-23-17-19-7-6-12-25(19)18-23/h2-3,8-9,19H,4-7,10-18H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	17.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Binding affinities against 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand in rat cerebral cortex membrane				J Med Chem 40: 2653-6 (1997) Article DOI: 10.1021/jm970216k BindingDB Entry DOI: 10.7270/Q2X34WKX
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Rattus norvegicus (Rat))	BDBM50059475 (2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...) Show SMILES COc1ccccc1N1CCN(CCCCN2CC3CCCN3C2)CC1 Show InChI InChI=1S/C21H34N4O/c1-26-21-9-3-2-8-20(21)24-15-13-22(14-16-24)10-4-5-11-23-17-19-7-6-12-25(19)18-23/h2-3,8-9,19H,4-7,10-18H2,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	72.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Binding affinities against Alpha-1 adrenergic receptor (alpha1 adrenoceptor) using [3H]-prazosin as radioligand in rat cerebral cortex membrane				J Med Chem 40: 2653-6 (1997) Article DOI: 10.1021/jm970216k BindingDB Entry DOI: 10.7270/Q2X34WKX
					More data for this Ligand-Target Pair