BDBM50059605 4-(1,8-Dihydroxy-9-oxo-9,10-dihydro-anthracen-2-ylmethyl)-N-hydroxy-benzamide::CHEMBL96929

SMILES: ONC(=O)c1ccc(Cc2ccc3Cc4cccc(O)c4C(=O)c3c2O)cc1

InChI Key: InChIKey=RDWSVVWNIJZOMI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50059605   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase (Bos taurus)	BDBM50059605 (4-(1,8-Dihydroxy-9-oxo-9,10-dihydro-anthracen-2-yl...) Show SMILES ONC(=O)c1ccc(Cc2ccc3Cc4cccc(O)c4C(=O)c3c2O)cc1 Show InChI InChI=1S/C22H17NO5/c24-17-3-1-2-14-11-15-8-9-16(20(25)19(15)21(26)18(14)17)10-12-4-6-13(7-5-12)22(27)23-28/h1-9,24-25,28H,10-11H2,(H,23,27)	PDB MMDB Reactome pathway B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Westfälische Wilhelms-Universität Münster Curated by ChEMBL					Assay Description 5-LO inhibitory activity, measured by production of 5-hydroxyeicosatetraenoic acid (5-HETE) and leukotriene B4 (LTB4) in bovine polymorphonuclear leu...				J Med Chem 40: 2780-7 (1997) Article DOI: 10.1021/jm9701785 BindingDB Entry DOI: 10.7270/Q28C9VB4
					More data for this Ligand-Target Pair