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BDBM50059613 2-(1,8-Dihydroxy-9-oxo-9,10-dihydro-anthracen-2-yl)-N-hydroxy-3-methyl-butyramide::CHEMBL96311

SMILES: CC(C)C(C(=O)NO)c1ccc2Cc3cccc(O)c3C(=O)c2c1O

InChI Key: InChIKey=BOQGERWXXRKMKH-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50059613   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Arachidonate 5-lipoxygenase


(Bos taurus)
BDBM50059613
PNG
(2-(1,8-Dihydroxy-9-oxo-9,10-dihydro-anthracen-2-yl...)
Show SMILES CC(C)C(C(=O)NO)c1ccc2Cc3cccc(O)c3C(=O)c2c1O
Show InChI InChI=1S/C19H19NO5/c1-9(2)14(19(24)20-25)12-7-6-11-8-10-4-3-5-13(21)15(10)18(23)16(11)17(12)22/h3-7,9,14,21-22,25H,8H2,1-2H3,(H,20,24)
PDB
MMDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 6.00E+3n/an/an/an/an/an/a



Westfälische Wilhelms-Universität Münster

Curated by ChEMBL


Assay Description
5-LO inhibitory activity, measured by production of 5-hydroxyeicosatetraenoic acid (5-HETE) and leukotriene B4 (LTB4) in bovine polymorphonuclear leu...


J Med Chem 40: 2780-7 (1997)


Article DOI: 10.1021/jm9701785
BindingDB Entry DOI: 10.7270/Q28C9VB4
More data for this
Ligand-Target Pair