BDBM50059674 (RS)-2-amino-3-[3-hydroxy-5-(1-methyl-2H-5-tetrazolyl)-4-isoxazolyl]propionic acid::2-Amino-3-[3-hydroxy-5-(1-methyl-1H-tetrazol-5-yl)-isoxazol-4-yl]-propionic acid::CHEMBL317790

SMILES: Cn1nnnc1-c1o[nH]c(=O)c1CC(N)C(O)=O

InChI Key: InChIKey=JLVXZYSVVWOWNA-UHFFFAOYSA-N

Data: 5 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50059674   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, kainate (Rattus norvegicus)	BDBM50059674 ((RS)-2-amino-3-[3-hydroxy-5-(1-methyl-2H-5-tetrazo...) Show SMILES Cn1nnnc1-c1o[nH]c(=O)c1CC(N)C(O)=O Show InChI InChI=1S/C8H10N6O4/c1-14-6(10-12-13-14)5-3(7(15)11-18-5)2-4(9)8(16)17/h4H,2,9H2,1H3,(H,11,15)(H,16,17)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a
The Danish University of Pharmaceutical Sciences Curated by ChEMBL					Assay Description In vitro activity of the compound at Ionotropic glutamate receptor using cortical wedge assays in rat brain synaptosoma				J Med Chem 48: 3438-42 (2005) Article DOI: 10.1021/jm050014l BindingDB Entry DOI: 10.7270/Q2H70FBJ
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic AMPA (Homo sapiens (Human))	BDBM50059674 ((RS)-2-amino-3-[3-hydroxy-5-(1-methyl-2H-5-tetrazo...) Show SMILES Cn1nnnc1-c1o[nH]c(=O)c1CC(N)C(O)=O Show InChI InChI=1S/C8H10N6O4/c1-14-6(10-12-13-14)5-3(7(15)11-18-5)2-4(9)8(16)17/h4H,2,9H2,1H3,(H,11,15)(H,16,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	3.00E+6	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Agonist activity at GluR4 expressed in HEK293 cells by Fluo-4/Ca2+ assay				J Med Chem 50: 4177-85 (2007) Article DOI: 10.1021/jm070532r BindingDB Entry DOI: 10.7270/Q29P32F3
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic AMPA (Homo sapiens (Human))	BDBM50059674 ((RS)-2-amino-3-[3-hydroxy-5-(1-methyl-2H-5-tetrazo...) Show SMILES Cn1nnnc1-c1o[nH]c(=O)c1CC(N)C(O)=O Show InChI InChI=1S/C8H10N6O4/c1-14-6(10-12-13-14)5-3(7(15)11-18-5)2-4(9)8(16)17/h4H,2,9H2,1H3,(H,11,15)(H,16,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+6	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Agonist activity at GluR3 expressed in HEK293 cells by Fluo-4/Ca2+ assay				J Med Chem 50: 4177-85 (2007) Article DOI: 10.1021/jm070532r BindingDB Entry DOI: 10.7270/Q29P32F3
					More data for this Ligand-Target Pair
GRIA1 (Homo sapiens (Human))	BDBM50059674 ((RS)-2-amino-3-[3-hydroxy-5-(1-methyl-2H-5-tetrazo...) Show SMILES Cn1nnnc1-c1o[nH]c(=O)c1CC(N)C(O)=O Show InChI InChI=1S/C8H10N6O4/c1-14-6(10-12-13-14)5-3(7(15)11-18-5)2-4(9)8(16)17/h4H,2,9H2,1H3,(H,11,15)(H,16,17)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+6	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Agonist activity at GluR1 expressed in HEK293 cells by Fluo-4/Ca2+ assay				J Med Chem 50: 4177-85 (2007) Article DOI: 10.1021/jm070532r BindingDB Entry DOI: 10.7270/Q29P32F3
					More data for this Ligand-Target Pair
GRIA2 (Homo sapiens (Human))	BDBM50059674 ((RS)-2-amino-3-[3-hydroxy-5-(1-methyl-2H-5-tetrazo...) Show SMILES Cn1nnnc1-c1o[nH]c(=O)c1CC(N)C(O)=O Show InChI InChI=1S/C8H10N6O4/c1-14-6(10-12-13-14)5-3(7(15)11-18-5)2-4(9)8(16)17/h4H,2,9H2,1H3,(H,11,15)(H,16,17)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+6	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Agonist activity at GluR2Q expressed in HEK293 cells by Fluo-4/Ca2+ assay				J Med Chem 50: 4177-85 (2007) Article DOI: 10.1021/jm070532r BindingDB Entry DOI: 10.7270/Q29P32F3
					More data for this Ligand-Target Pair