BDBM50060369 3-Acetoxymethyl-7-dibromomethylene-5,5,8-trioxo-5lambda*6*-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester::CHEMBL334282

SMILES: [#6]-[#6](=O)-[#8]-[#6]-[#6]-1=[#6](-[#7]-2-[#6](\[#6](=[#6](\Br)Br)-[#6]-2=O)S(=O)(=O)[#6]-1)-[#6](=O)-[#8]-[#6](-c1ccccc1)-c1ccccc1

InChI Key: InChIKey=OPWQURYRMSLMBL-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50060369   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Pancreatic elastase (Sus scrofa)	BDBM50060369 (3-Acetoxymethyl-7-dibromomethylene-5,5,8-trioxo-5l...) Show SMILES [#6]-[#6](=O)-[#8]-[#6]-[#6]-1=[#6](-[#7]-2-[#6](\[#6](=[#6](\Br)Br)-[#6]-2=O)S(=O)(=O)[#6]-1)-[#6](=O)-[#8]-[#6](-c1ccccc1)-c1ccccc1 |t:5| Show InChI InChI=1S/C24H19Br2NO7S/c1-14(28)33-12-17-13-35(31,32)23-18(21(25)26)22(29)27(23)19(17)24(30)34-20(15-8-4-2-5-9-15)16-10-6-3-7-11-16/h2-11,20,23H,12-13H2,1H3	MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.80E+6	n/a	n/a	n/a	n/a	n/a	n/a
Southern Methodist University Curated by ChEMBL					Assay Description Inhibition of porcine pancreatic elastase				J Med Chem 40: 3423-33 (1997) Article DOI: 10.1021/jm970351x BindingDB Entry DOI: 10.7270/Q22R3QRH
					More data for this Ligand-Target Pair
Leukocyte elastase (Homo sapiens (Human))	BDBM50060369 (3-Acetoxymethyl-7-dibromomethylene-5,5,8-trioxo-5l...) Show SMILES [#6]-[#6](=O)-[#8]-[#6]-[#6]-1=[#6](-[#7]-2-[#6](\[#6](=[#6](\Br)Br)-[#6]-2=O)S(=O)(=O)[#6]-1)-[#6](=O)-[#8]-[#6](-c1ccccc1)-c1ccccc1 |t:5| Show InChI InChI=1S/C24H19Br2NO7S/c1-14(28)33-12-17-13-35(31,32)23-18(21(25)26)22(29)27(23)19(17)24(30)34-20(15-8-4-2-5-9-15)16-10-6-3-7-11-16/h2-11,20,23H,12-13H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.07E+6	n/a	n/a	n/a	n/a	n/a	n/a
Southern Methodist University Curated by ChEMBL					Assay Description Inhibition of human leukocyte elastase				J Med Chem 40: 3423-33 (1997) Article DOI: 10.1021/jm970351x BindingDB Entry DOI: 10.7270/Q22R3QRH
					More data for this Ligand-Target Pair