BDBM50060527 CHEMBL3394454

SMILES: Nc1noc2cccc(-c3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)c(Cl)c4)cc3)c12

InChI Key: InChIKey=VYZYJWSPDQTUJR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50060527   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50060527 (CHEMBL3394454) Show SMILES Nc1noc2cccc(-c3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)c(Cl)c4)cc3)c12 Show InChI InChI=1S/C24H18ClFN4O3/c25-17-12-15(8-9-18(17)26)29-23(32)24(10-11-24)22(31)28-14-6-4-13(5-7-14)16-2-1-3-19-20(16)21(27)30-33-19/h1-9,12H,10-11H2,(H2,27,30)(H,28,31)(H,29,32)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of purified recombinant c-MET (unknown origin) using poly (Glu, Tyr) substrate after 60 mins by ELISA				Bioorg Med Chem 23: 564-78 (2015) Article DOI: 10.1016/j.bmc.2014.12.002 BindingDB Entry DOI: 10.7270/Q2VT1TRT
					More data for this Ligand-Target Pair