BDBM50060684 9-Fluoro-4-piperazin-1-yl-pyrrolo[1,2-a]quinoxaline::CHEMBL331304

SMILES: Fc1cccc2nc(N3CCNCC3)c3cccn3c12

InChI Key: InChIKey=WTIHQLOVALBPDM-UHFFFAOYSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50060684   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serotonin 1B/1D receptor (Rattus norvegicus (Rat))	BDBM50060684 (9-Fluoro-4-piperazin-1-yl-pyrrolo[1,2-a]quinoxalin...) Show SMILES Fc1cccc2nc(N3CCNCC3)c3cccn3c12 Show InChI InChI=1S/C15H15FN4/c16-11-3-1-4-12-14(11)20-8-2-5-13(20)15(18-12)19-9-6-17-7-10-19/h1-5,8,17H,6-7,9-10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	106	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Siena Curated by ChEMBL					Assay Description Inhibition of radiolabeled [3H]-5-HT ligand binding to 5-hydroxytryptamine 1B receptor				J Med Chem 40: 3670-8 (1997) Article DOI: 10.1021/jm970376w BindingDB Entry DOI: 10.7270/Q24Q7VP2
					More data for this Ligand-Target Pair
HTR4 (RAT)	BDBM50060684 (9-Fluoro-4-piperazin-1-yl-pyrrolo[1,2-a]quinoxalin...) Show SMILES Fc1cccc2nc(N3CCNCC3)c3cccn3c12 Show InChI InChI=1S/C15H15FN4/c16-11-3-1-4-12-14(11)20-8-2-5-13(20)15(18-12)19-9-6-17-7-10-19/h1-5,8,17H,6-7,9-10H2	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Siena Curated by ChEMBL					Assay Description Inhibition of radiolabeled [3H]GR-113808 ligand binding to 5-hydroxytryptamine 4 receptor				J Med Chem 40: 3670-8 (1997) Article DOI: 10.1021/jm970376w BindingDB Entry DOI: 10.7270/Q24Q7VP2
					More data for this Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C) (Rattus norvegicus (Rat))	BDBM50060684 (9-Fluoro-4-piperazin-1-yl-pyrrolo[1,2-a]quinoxalin...) Show SMILES Fc1cccc2nc(N3CCNCC3)c3cccn3c12 Show InChI InChI=1S/C15H15FN4/c16-11-3-1-4-12-14(11)20-8-2-5-13(20)15(18-12)19-9-6-17-7-10-19/h1-5,8,17H,6-7,9-10H2	KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	784	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Siena Curated by ChEMBL					Assay Description Inhibition of radiolabeled [3H]mesulergine ligand binding to 5-hydroxytryptamine 2C receptor				J Med Chem 40: 3670-8 (1997) Article DOI: 10.1021/jm970376w BindingDB Entry DOI: 10.7270/Q24Q7VP2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50060684 (9-Fluoro-4-piperazin-1-yl-pyrrolo[1,2-a]quinoxalin...) Show SMILES Fc1cccc2nc(N3CCNCC3)c3cccn3c12 Show InChI InChI=1S/C15H15FN4/c16-11-3-1-4-12-14(11)20-8-2-5-13(20)15(18-12)19-9-6-17-7-10-19/h1-5,8,17H,6-7,9-10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	761	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Siena Curated by ChEMBL					Assay Description Inhibition of radiolabeled [3H]-Ketanserin ligand binding to 5-hydroxytryptamine 2A receptor				J Med Chem 40: 3670-8 (1997) Article DOI: 10.1021/jm970376w BindingDB Entry DOI: 10.7270/Q24Q7VP2
					More data for this Ligand-Target Pair
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor (Rattus norvegicus-RAT)	BDBM50060684 (9-Fluoro-4-piperazin-1-yl-pyrrolo[1,2-a]quinoxalin...) Show SMILES Fc1cccc2nc(N3CCNCC3)c3cccn3c12 Show InChI InChI=1S/C15H15FN4/c16-11-3-1-4-12-14(11)20-8-2-5-13(20)15(18-12)19-9-6-17-7-10-19/h1-5,8,17H,6-7,9-10H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.90	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Siena Curated by ChEMBL					Assay Description Inhibition of [3H]BRL-43694 binding to 5-hydroxytryptamine 3 receptor of rat cortical homogenate.				J Med Chem 40: 3670-8 (1997) Article DOI: 10.1021/jm970376w BindingDB Entry DOI: 10.7270/Q24Q7VP2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50060684 (9-Fluoro-4-piperazin-1-yl-pyrrolo[1,2-a]quinoxalin...) Show SMILES Fc1cccc2nc(N3CCNCC3)c3cccn3c12 Show InChI InChI=1S/C15H15FN4/c16-11-3-1-4-12-14(11)20-8-2-5-13(20)15(18-12)19-9-6-17-7-10-19/h1-5,8,17H,6-7,9-10H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	268	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Siena Curated by ChEMBL					Assay Description Inhibition of radiolabeled [3H]-8-OH-DPAT ligand binding to 5-hydroxytryptamine 1A receptor				J Med Chem 40: 3670-8 (1997) Article DOI: 10.1021/jm970376w BindingDB Entry DOI: 10.7270/Q24Q7VP2
					More data for this Ligand-Target Pair