BDBM50060722 2-[1,4']Bipiperidinyl-1'-yl-1-[2-(4-chloro-phenoxymethyl)-1-methyl-1H-indol-3-yl]-ethanone::CHEMBL124343

SMILES: Cn1c(COc2ccc(Cl)cc2)c(C(=O)CN2CCC(CC2)N2CCCCC2)c2ccccc12

InChI Key: InChIKey=USPYPWGLVYWPCV-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50060722   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuropeptide Y receptor type 1 (Homo sapiens (Human))	BDBM50060722 (2-[1,4']Bipiperidinyl-1'-yl-1-[2-(4-chloro-phenoxy...) Show SMILES Cn1c(COc2ccc(Cl)cc2)c(C(=O)CN2CCC(CC2)N2CCCCC2)c2ccccc12 Show InChI InChI=1S/C28H34ClN3O2/c1-30-25-8-4-3-7-24(25)28(26(30)20-34-23-11-9-21(29)10-12-23)27(33)19-31-17-13-22(14-18-31)32-15-5-2-6-16-32/h3-4,7-12,22H,2,5-6,13-20H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Binding affinity for Neuropeptide Y receptor type 1 expressed in AV-12 cells				J Med Chem 40: 3712-4 (1997) Article DOI: 10.1021/jm970512x BindingDB Entry DOI: 10.7270/Q2HQ3Z1P
					More data for this Ligand-Target Pair
PPYR1 (Homo sapiens (Human))	BDBM50060722 (2-[1,4']Bipiperidinyl-1'-yl-1-[2-(4-chloro-phenoxy...) Show SMILES Cn1c(COc2ccc(Cl)cc2)c(C(=O)CN2CCC(CC2)N2CCCCC2)c2ccccc12 Show InChI InChI=1S/C28H34ClN3O2/c1-30-25-8-4-3-7-24(25)28(26(30)20-34-23-11-9-21(29)10-12-23)27(33)19-31-17-13-22(14-18-31)32-15-5-2-6-16-32/h3-4,7-12,22H,2,5-6,13-20H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Affinity for human Neuropeptide Y receptor type 4				J Med Chem 40: 3712-4 (1997) Article DOI: 10.1021/jm970512x BindingDB Entry DOI: 10.7270/Q2HQ3Z1P
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 2 (Homo sapiens (Human))	BDBM50060722 (2-[1,4']Bipiperidinyl-1'-yl-1-[2-(4-chloro-phenoxy...) Show SMILES Cn1c(COc2ccc(Cl)cc2)c(C(=O)CN2CCC(CC2)N2CCCCC2)c2ccccc12 Show InChI InChI=1S/C28H34ClN3O2/c1-30-25-8-4-3-7-24(25)28(26(30)20-34-23-11-9-21(29)10-12-23)27(33)19-31-17-13-22(14-18-31)32-15-5-2-6-16-32/h3-4,7-12,22H,2,5-6,13-20H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Affinity for human Neuropeptide Y receptor type 2				J Med Chem 40: 3712-4 (1997) Article DOI: 10.1021/jm970512x BindingDB Entry DOI: 10.7270/Q2HQ3Z1P
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 5 ( NPY Y5) (Homo sapiens (Human))	BDBM50060722 (2-[1,4']Bipiperidinyl-1'-yl-1-[2-(4-chloro-phenoxy...) Show SMILES Cn1c(COc2ccc(Cl)cc2)c(C(=O)CN2CCC(CC2)N2CCCCC2)c2ccccc12 Show InChI InChI=1S/C28H34ClN3O2/c1-30-25-8-4-3-7-24(25)28(26(30)20-34-23-11-9-21(29)10-12-23)27(33)19-31-17-13-22(14-18-31)32-15-5-2-6-16-32/h3-4,7-12,22H,2,5-6,13-20H2,1H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Affinity for human Neuropeptide Y receptor type 5				J Med Chem 40: 3712-4 (1997) Article DOI: 10.1021/jm970512x BindingDB Entry DOI: 10.7270/Q2HQ3Z1P
					More data for this Ligand-Target Pair