null
SMILES: COc1ccc(CCNC[C@H](O)CN2CN(c3ccc(F)cc3)C3(CCN(CC4CCCCCCC4)CC3)C2=O)cc1OC
InChI Key: InChIKey=ABBBAYMZEUIFIL-HKBQPEDESA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Nociceptin receptor (Homo sapiens (Human)) | BDBM50060893 (CHEMBL3394753) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.80 | n/a | n/a | n/a | n/a | n/a | n/a |
West Chester University Curated by ChEMBL | Assay Description Displacement of [125I]-Tyr14-nociceptin from human ORL1 expressed in HEK293 cells after 2 hrs by scintillation counting | Bioorg Med Chem Lett 25: 602-6 (2015) Article DOI: 10.1016/j.bmcl.2014.12.015 BindingDB Entry DOI: 10.7270/Q23B61S0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM50060893 (CHEMBL3394753) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
West Chester University Curated by ChEMBL | Assay Description Displacement of [3H]U69,593 from human kappa opioid receptor expressed in HEK293 cells after 2 hrs by scintillation counting | Bioorg Med Chem Lett 25: 602-6 (2015) Article DOI: 10.1016/j.bmcl.2014.12.015 BindingDB Entry DOI: 10.7270/Q23B61S0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Homo sapiens (Human)) | BDBM50060893 (CHEMBL3394753) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 990 | n/a | n/a | n/a | n/a | n/a | n/a |
West Chester University Curated by ChEMBL | Assay Description Displacement of [3H]DAMGO from human Mu opioid receptor expressed in HEK293 cells after 2 hrs by scintillation counting | Bioorg Med Chem Lett 25: 602-6 (2015) Article DOI: 10.1016/j.bmcl.2014.12.015 BindingDB Entry DOI: 10.7270/Q23B61S0 | |||||||||||
More data for this Ligand-Target Pair |