BDBM50060976 (3-Phenoxy-phenyl)-acetic acid::CHEMBL107066
SMILES: OC(=O)Cc1cccc(Oc2ccccc2)c1
InChI Key: InChIKey=LEMRHTTWKDVQEI-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Human papillomavirus regulatory protein E2 (Human papillomavirus type 16) | BDBM50060976 ((3-Phenoxy-phenyl)-acetic acid | CHEMBL107066) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | >1.00E+7 | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Dissociation constant after binding to human papillomavirus E2 DNA-binding domain (DBD) by observing the changes in [15N]-HSQC spectra. | J Med Chem 40: 3144-50 (1997) Article DOI: 10.1021/jm9703404 BindingDB Entry DOI: 10.7270/Q2MG7NN2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclooxygenase-2 (COX-2) (Mus musculus (Mouse)) | BDBM50060976 ((3-Phenoxy-phenyl)-acetic acid | CHEMBL107066) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 6.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of mouse COX2-mediated 2-arachidonoylglycerol oxygenation preincubated for 3 mins before 2-arachidonoylglycerol addition measured after 30... | ACS Med Chem Lett 3: 759-763 (2012) Article DOI: 10.1021/ml3001616 BindingDB Entry DOI: 10.7270/Q2FJ2HWS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma hydroxybutyric, GHB (RAT) | BDBM50060976 ((3-Phenoxy-phenyl)-acetic acid | CHEMBL107066) | UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.63E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland Curated by ChEMBL | Assay Description Displacement of [3H]-NCS-382 (16 nM) from GHB receptor of rat cerebrocortical membranes | Bioorg Med Chem Lett 15: 3201-2 (2005) Article DOI: 10.1016/j.bmcl.2005.05.011 BindingDB Entry DOI: 10.7270/Q2MP52TK | |||||||||||
More data for this Ligand-Target Pair |