BDBM50061009 CHEMBL3393555

SMILES: CN1CCN(CC1)c1cnnc(NC2CC3CCC2C3)c1

InChI Key: InChIKey=QAXRJLAQFRQDQS-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50061009   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H4 receptor (Homo sapiens (Human))	BDBM50061009 (CHEMBL3393555) Show SMILES CN1CCN(CC1)c1cnnc(NC2CC3CCC2C3)c1 Show InChI InChI=1S/C16H25N5/c1-20-4-6-21(7-5-20)14-10-16(19-17-11-14)18-15-9-12-2-3-13(15)8-12/h10-13,15H,2-9H2,1H3,(H,18,19)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	365	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development, LLC Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human recombinant histamine H4 receptor				Bioorg Med Chem Lett 25: 956-9 (2015) Article DOI: 10.1016/j.bmcl.2014.12.027 BindingDB Entry DOI: 10.7270/Q2639RDD
					More data for this Ligand-Target Pair