BDBM50061203 (R)-3-(4-Ethyl-3-iodo-phenyl)-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester::CHEMBL127623

SMILES: CCc1ccc(cc1I)C1CC2CCC(N2)C1C(=O)OC

InChI Key: InChIKey=BSMPOYNWUIFFDN-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50061203   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Norepinephrine Monoamine transporters (Rattus norvegicus)	BDBM50061203 ((R)-3-(4-Ethyl-3-iodo-phenyl)-8-aza-bicyclo[3.2.1]...) Show SMILES CCc1ccc(cc1I)C1CC2CCC(N2)C1C(=O)OC |THB:5:9:15:13.12,17:16:15:13.12| Show InChI InChI=1S/C17H22INO2/c1-3-10-4-5-11(8-14(10)18)13-9-12-6-7-15(19-12)16(13)17(20)21-2/h4-5,8,12-13,15-16,19H,3,6-7,9H2,1-2H3	Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	148	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description In vitro inhibitory activity against radioligand [3H]-nisoxatine binding to norepinephrine transporter (NET) in rat cortical tissue				J Med Chem 40: 3861-4 (1998) Article DOI: 10.1021/jm970492z BindingDB Entry DOI: 10.7270/Q2GX4C7G
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50061203 ((R)-3-(4-Ethyl-3-iodo-phenyl)-8-aza-bicyclo[3.2.1]...) Show SMILES CCc1ccc(cc1I)C1CC2CCC(N2)C1C(=O)OC |THB:5:9:15:13.12,17:16:15:13.12| Show InChI InChI=1S/C17H22INO2/c1-3-10-4-5-11(8-14(10)18)13-9-12-6-7-15(19-12)16(13)17(20)21-2/h4-5,8,12-13,15-16,19H,3,6-7,9H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.690	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description In vitro inhibitory activity against radioligand [3H]paroxetine binding to serotonin transporter (5-HTT) in rat midbrain tissue				J Med Chem 40: 3861-4 (1998) Article DOI: 10.1021/jm970492z BindingDB Entry DOI: 10.7270/Q2GX4C7G
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50061203 ((R)-3-(4-Ethyl-3-iodo-phenyl)-8-aza-bicyclo[3.2.1]...) Show SMILES CCc1ccc(cc1I)C1CC2CCC(N2)C1C(=O)OC |THB:5:9:15:13.12,17:16:15:13.12| Show InChI InChI=1S/C17H22INO2/c1-3-10-4-5-11(8-14(10)18)13-9-12-6-7-15(19-12)16(13)17(20)21-2/h4-5,8,12-13,15-16,19H,3,6-7,9H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	329	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description In vitro inhibitory activity against radioligand [3H]-WN 35,428 binding to dopamine transporter (DAT) in rat striatal tissue				J Med Chem 40: 3861-4 (1998) Article DOI: 10.1021/jm970492z BindingDB Entry DOI: 10.7270/Q2GX4C7G
					More data for this Ligand-Target Pair