BDBM50061247 1-(4-fluorophenyl)-4-spiro[2,3-dihydro-1H-indene-1,4'-(hexahydropyridine)]-1-yl-1-butanone::CHEMBL341139

SMILES: Fc1ccc(cc1)C(=O)CCCN1CCC2(CCc3ccccc23)CC1

InChI Key: InChIKey=DGDSZKSHJGFASX-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50061247   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50061247 (1-(4-fluorophenyl)-4-spiro[2,3-dihydro-1H-indene-1...) Show SMILES Fc1ccc(cc1)C(=O)CCCN1CCC2(CCc3ccccc23)CC1 Show InChI InChI=1S/C23H26FNO/c24-20-9-7-19(8-10-20)22(26)6-3-15-25-16-13-23(14-17-25)12-11-18-4-1-2-5-21(18)23/h1-2,4-5,7-10H,3,6,11-17H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Sigma-1 binding assay was done in guinea pig membranes by labelling the binding site with [3H]-(+)-pentazocine				J Med Chem 40: 3905-14 (1998) Article DOI: 10.1021/jm970326r BindingDB Entry DOI: 10.7270/Q2KK99WJ
					More data for this Ligand-Target Pair
Vesicular acetylcholine transporter (Homo sapiens (Human))	BDBM50061247 (1-(4-fluorophenyl)-4-spiro[2,3-dihydro-1H-indene-1...) Show SMILES Fc1ccc(cc1)C(=O)CCCN1CCC2(CCc3ccccc23)CC1 Show InChI InChI=1S/C23H26FNO/c24-20-9-7-19(8-10-20)22(26)6-3-15-25-16-13-23(14-17-25)12-11-18-4-1-2-5-21(18)23/h1-2,4-5,7-10H,3,6,11-17H2	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	85	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Binding to vesicular acetylcholine transporter of torpedo synaptic vesicles				J Med Chem 40: 3905-14 (1998) Article DOI: 10.1021/jm970326r BindingDB Entry DOI: 10.7270/Q2KK99WJ
					More data for this Ligand-Target Pair